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韩国核电厂附近成年居民的癌症风险-1992-2010 年的队列研究。

Cancer risk in adult residents near nuclear power plants in Korea - a cohort study of 1992-2010.

机构信息

Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.

出版信息

J Korean Med Sci. 2012 Sep;27(9):999-1008. doi: 10.3346/jkms.2012.27.9.999. Epub 2012 Aug 22.

Abstract

This study evaluated cancer risk for adult residents near Nuclear Power Plants (NPPs) in Korea through a valid prospective cohort study during 1992-2010. The study cohort was composed of 11,367 adults living within a five km radius from the NPPs for the exposed and 24,809 adults for the non-exposed or reference cohort set at two different levels of proximity; 5-30 km radius and more than 30 km radius away from NPPs. In 303,542.5 person-years of follow-up, a total of 2,298 cancer cases of all sites, or 1,377 radio-inducible cancers diagnosed during 1992-2008 were ascertained. Multiple adjusted hazard ratios and 95% confidence intervals were estimated using multivariate Cox proportional hazard model. There were no epidemiological evidence for increased risk of cancer due to radiation from NPPs. Radiological study results or surveillance data of radiation doses around NPPs could be well documented for risk estimation of radio-inducible cancers, instead of epidemiological study results of the long-time required. Continuous surveillance of quantitative measures of dose levels around NPPs and radiation exposures to the residents is warranted.

摘要

本研究通过 1992 年至 2010 年期间进行的一项有效的前瞻性队列研究,评估了韩国核电站(NPP)附近成年居民的癌症风险。研究队列由居住在核电站五公里半径范围内的 11367 名成年人(暴露组)和 24809 名成年人(非暴露组或参考组)组成,他们与核电站的距离设定为两个不同的级别:五至三十公里半径和三十公里以上。在 303542.5 人年的随访中,共确定了 2298 例所有部位的癌症病例,或 1992 年至 2008 年期间诊断出的 1377 例放射性诱导癌症。使用多变量 Cox 比例风险模型估计了多个调整后的风险比和 95%置信区间。没有流行病学证据表明核电站辐射会增加癌症风险。可以很好地记录核电站周围的放射学研究结果或辐射剂量监测数据,以用于放射性诱导癌症的风险估计,而无需进行长时间的流行病学研究。需要对核电站周围剂量水平的定量测量和居民的辐射暴露进行持续监测。

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