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射波刀在高危中枢神经系统肿瘤中的临床应用:60例临床试验报告

Clinical application of CyberKnife for high-risk central nervous system tumors: A clinical trial report of 60 cases.

作者信息

Wang Xin, Wang Yuan-Yuan, Jiang Peng, Ma Jian-Jun, Qu Zhen, Liu Han-Chen, Wang Shan-Shan, Wang Yi-Shan

机构信息

Center for Non-Traumatic Treatment and Diagnosis of Tumors, The People's Liberation Army 107th Hospital, Affiliated Hospital of Bin Zhou Medical College, Shandong 264002, P.R. China.

出版信息

Exp Ther Med. 2012 Jan;3(1):105-108. doi: 10.3892/etm.2011.356. Epub 2011 Sep 23.

Abstract

The objective of the present study was to evaluate the application potential of CyberKnife for high-risk tumors of the central nervous system and to analyze the effectiveness of CyberKnife in relation to dose recovery and gain division (times). A total of Eighty-one targeted areas from 139 central nervous tumor lesions in 60 patients were treated with I-VI ranged CyberKnife for 1 week. Following CyberKnife treatment, imaging tests revealed a decrease in tumor volume, reduction of central nervous system symptoms and an increase in the life quality of patients. The advantages of CyberKnife include non-invasiveness, individualized treatment, flexibility, high accuracy and rapid treatment. CyberKnife produces slight damage and a favorable therapeutic effect and expands our concepts concerning precise radiotherapy for tumors. It is an indispensable method for personalized tumor treatment.

摘要

本研究的目的是评估射波刀在中枢神经系统高危肿瘤中的应用潜力,并分析射波刀在剂量恢复和增益分割(次数)方面的有效性。对60例患者139个中枢神经肿瘤病灶的81个靶向区域采用I-VI级射波刀进行了为期1周的治疗。射波刀治疗后,影像学检查显示肿瘤体积减小,中枢神经系统症状减轻,患者生活质量提高。射波刀的优点包括无创、个体化治疗、灵活性高、精度高和治疗速度快。射波刀造成的损伤轻微,治疗效果良好,拓展了我们对肿瘤精确放疗的认识。它是个性化肿瘤治疗不可或缺的方法。

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