Academic Radiotherapy Departement, CLCC Oscar Lambret, University Lille II, Lille, France.
Crit Rev Oncol Hematol. 2011 Sep;79(3):308-14. doi: 10.1016/j.critrevonc.2010.09.006. Epub 2010 Dec 13.
The relatively recent introduction of CyberKnife® in the field of radiotherapy has prompted the question of accessibility and usefulness of this technique for seniors. From June 2007 to June 2009, we treated 345 patients of all ages with CyberKnife as part of a single-center study. Median age was 61 years (range, 8-86 years). Ninety-eight patients were over 70 and 17 were older than 80. The treatment could not be completed with 2% (2/98) patients over 70 vs. 3.6% (9/247) among the younger (ns). Physiologic or psychologic problems in maintaining position for a long time were not more frequent among those over 70. The same was true with those over 80. Patients over 70 years old are able to tolerate CyberKnife treatment as efficiently as their younger counterparts. Elderly patients should not be restricted from access to CyberKnife radiosurgery with curative intent.
CyberKnife® 在放射治疗领域的应用相对较新,这引发了一个问题,即对于老年人来说,这种技术是否具有可及性和实用性。2007 年 6 月至 2009 年 6 月,我们在一项单中心研究中用 CyberKnife 治疗了 345 名不同年龄的患者。中位年龄为 61 岁(范围:8-86 岁)。98 名患者年龄超过 70 岁,17 名患者年龄超过 80 岁。有 2%(2/98)的 70 岁以上患者和 3.6%(9/247)的 70 岁以下患者(无统计学差异)无法完成治疗。对于那些 70 岁以上的患者,长时间保持治疗体位所导致的生理或心理问题并不比年轻患者更常见。80 岁以上的患者也是如此。70 岁以上的患者能够像他们年轻的患者一样高效地耐受 CyberKnife 治疗。对于有治愈意图的 CyberKnife 放射外科治疗,老年患者不应被限制使用。