Suppr超能文献

老年患者的甲状腺手术:他们的手术风险会增加吗?

Thyroid surgery for elderly patients: are they at increased operative risks?

作者信息

Ng Sze-How, Wong Kai-Pun, Lang Brian Hung-Hin

机构信息

Breast and Endocrine Unit, Department of Surgery, Kuala Lumpur Hospital, 50586 Kuala Lumpur, Malaysia.

出版信息

J Thyroid Res. 2012;2012:946276. doi: 10.1155/2012/946276. Epub 2012 Aug 16.

Abstract

An increasing elderly population, a rising incidence of differentiated thyroid carcinoma (DTC), and a rising incidence of benign nodular disease with age are all contributing to a rise in thyroid operations for the elderly. Literature review on the outcome and safety of thyroid surgery in elderly patients has been filled with conflicting results and this subject remains controversial. Although most single-institution studies conducted by high-volume surgeons did not find significant differences of complication rates in elderly when compared with younger cohorts, they often lacked the power necessary to identify subtle differences and suffered from various selection and referral biases. Recent evidence from large population-based studies concluded that thyroid surgery in the elderly was associated with higher complication rates. One of the major contributing factors for the increased complication rate was because most elderly patients suffered from many preexisting comorbidities. Therefore, elderly patients who have abnormal thyroid findings should complete a thorough preoperative workup and better postoperative care after undergoing any thyroid surgery. Furthermore, these high-risk patients would benefit if they could be referred to high-volume, specialized surgical units early. In this systemic review, we aimed to evaluate different issues and controversies in thyroidectomy for elderly patients.

摘要

老年人口不断增加、分化型甲状腺癌(DTC)发病率上升以及良性结节性疾病发病率随年龄增长而上升,这些都导致了老年甲状腺手术量的增加。关于老年患者甲状腺手术结果和安全性的文献综述结果相互矛盾,这一话题仍存在争议。尽管大多数由高手术量外科医生进行的单机构研究未发现老年患者与年轻患者在并发症发生率上有显著差异,但这些研究往往缺乏识别细微差异所需的能力,且存在各种选择和转诊偏倚。基于大量人群研究的最新证据表明,老年患者的甲状腺手术与更高的并发症发生率相关。并发症发生率增加的一个主要因素是,大多数老年患者患有多种并存的合并症。因此,甲状腺检查结果异常的老年患者在接受任何甲状腺手术后,都应进行全面的术前检查并接受更好的术后护理。此外,如果这些高危患者能够尽早转诊至高手术量的专业外科科室,他们将从中受益。在本系统综述中,我们旨在评估老年患者甲状腺切除术的不同问题和争议。

相似文献

1
Thyroid surgery for elderly patients: are they at increased operative risks?
J Thyroid Res. 2012;2012:946276. doi: 10.1155/2012/946276. Epub 2012 Aug 16.
4
Thyroid surgery in octogenarians is associated with higher complication rates.
Surgery. 2009 Nov;146(5):913-21. doi: 10.1016/j.surg.2009.05.004.
6
What is the effect of age on pancreatic resection?
Adv Surg. 2009;43:233-49. doi: 10.1016/j.yasu.2009.02.004.
7
A population-based prospective cohort study of complications after thyroidectomy in the elderly.
J Clin Endocrinol Metab. 2012 May;97(5):1645-53. doi: 10.1210/jc.2011-1162. Epub 2012 Mar 14.
9
Surgical options for thyroid cancer and post-surgical management.
Expert Rev Endocrinol Metab. 2018 May;13(3):137-148. doi: 10.1080/17446651.2018.1464910. Epub 2018 Apr 20.

引用本文的文献

本文引用的文献

1
A population-based prospective cohort study of complications after thyroidectomy in the elderly.
J Clin Endocrinol Metab. 2012 May;97(5):1645-53. doi: 10.1210/jc.2011-1162. Epub 2012 Mar 14.
2
Quality of life is not influenced by the extent of surgery in patients with benign goiter.
Langenbecks Arch Surg. 2011 Dec;396(8):1157-63. doi: 10.1007/s00423-011-0822-7. Epub 2011 Aug 2.
4
Global cancer statistics.
CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90. doi: 10.3322/caac.20107. Epub 2011 Feb 4.
5
Technological innovations in surgical approach for thyroid cancer.
J Oncol. 2010;2010. doi: 10.1155/2010/490719. Epub 2010 Jul 27.
6
Rehospitalization among elderly patients with thyroid cancer after thyroidectomy are prevalent and costly.
Ann Surg Oncol. 2010 Nov;17(11):2816-23. doi: 10.1245/s10434-010-1144-7. Epub 2010 Jun 15.
7
Long-term efficacy of lymph node reoperation for persistent papillary thyroid cancer.
J Clin Endocrinol Metab. 2010 May;95(5):2187-94. doi: 10.1210/jc.2010-0063. Epub 2010 Mar 23.
8
Treatment patterns of aging Americans with differentiated thyroid cancer.
Cancer. 2010 Jan 1;116(1):20-30. doi: 10.1002/cncr.24717.
10
Geriatric thyroidectomy: safety of thyroid surgery in an aging population.
Arch Otolaryngol Head Neck Surg. 2009 Oct;135(10):1041-4. doi: 10.1001/archoto.2009.138.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验