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生活质量不受良性甲状腺肿患者手术范围的影响。

Quality of life is not influenced by the extent of surgery in patients with benign goiter.

机构信息

University Hospital of General, Visceral and Transplantation Surgery of Heidelberg, Heidelberg, Germany.

出版信息

Langenbecks Arch Surg. 2011 Dec;396(8):1157-63. doi: 10.1007/s00423-011-0822-7. Epub 2011 Aug 2.

Abstract

INTRODUCTION

The surgical approach to benign goiter is becoming increasingly radical due to the risk of recurrent goiter. The aim of this prospective study was to evaluate the impact of surgery on health-related quality of life (HRQoL) of patients with benign goiter.

MATERIAL AND METHODS

HRQoL data from 115 patients with benign goiter were analyzed. Thirty-three patients (group 1) had a hemithyroidectomy. Sixty-five patients (group 2) had a so-called Dunhill operation (hemithyroidectomy + near-total thyroidectomy of the opposite side), and in 17 patients, a total resection of the goiter was performed. The validated HRQoL instrument, the EuroQol-5D, was applied to measure the health-related quality of life.

RESULTS

With an overall complication rate of 10% and no permanent recurrent laryngeal nerve palsy, it was shown that surgery for benign goiter is safe. In the validated HRQoL questionnaire (EQ-5D), no significant variance could be found between different surgical procedures such as thyroidectomy, hemithyroidectomy, or Dunhill procedure. Further, no significant differences in QoL were found in EQ-5D questionnaire compared to normal population.

CONCLUSION

Thyroid surgery can be done safely and without impairment of life quality, regardless of the extent of the operation.

摘要

简介

由于复发性甲状腺肿的风险,良性甲状腺肿的手术方法变得越来越激进。本前瞻性研究的目的是评估手术对良性甲状腺肿患者健康相关生活质量(HRQoL)的影响。

材料和方法

分析了 115 例良性甲状腺肿患者的 HRQoL 数据。33 例患者(组 1)行甲状腺叶切除术。65 例患者(组 2)行所谓的邓希尔手术(甲状腺叶切除术+对侧近全甲状腺切除术),17 例患者行甲状腺肿全切除术。应用经过验证的 HRQoL 工具,即欧洲五维健康量表(EQ-5D)来衡量健康相关生活质量。

结果

总体并发症发生率为 10%,且无永久性喉返神经麻痹,表明良性甲状腺肿手术是安全的。在经过验证的 HRQoL 问卷(EQ-5D)中,甲状腺切除术、甲状腺叶切除术或邓希尔手术等不同手术方法之间没有显著的差异。此外,与正常人群相比,EQ-5D 问卷在 QoL 方面没有显著差异。

结论

无论手术范围如何,甲状腺手术都可以安全进行,且不会损害生活质量。

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