Department of Psychology, Queens College, City University of New York, Flushing, NY 11367, USA.
Expert Rev Respir Med. 2012 Aug;6(4):397-406. doi: 10.1586/ers.12.34.
Asthma and mental health problems, such as depression, anxiety and behavior disorders, are common among youth and are significant sources of morbidity. There is a consistent association between asthma and anxiety/depression and a less consistent association between asthma and behavior disorders. Possible biological and psychological mechanisms may include inflammatory processes as well as the stress of having to live with a life-threatening condition. Future studies are warranted with longitudinal designs to establish temporality as well as measures of potential confounds. Biological and psychological measures would complement the longitudinal design to further establish causality. In addition, more information on the degree to which asthma and mental health have reciprocal influences on each other over time - and the mechanisms of these relationships - are needed in order to develop more effective intervention strategies to improve asthma control and mental health among those with both.
哮喘和精神健康问题，如抑郁、焦虑和行为障碍，在年轻人中很常见，是发病率的重要来源。哮喘与焦虑/抑郁之间存在一致的关联，而哮喘与行为障碍之间的关联则不那么一致。可能的生物学和心理机制包括炎症过程以及不得不患有危及生命的疾病的压力。未来的研究需要采用纵向设计来确定时间性以及潜在混杂因素的测量。生物学和心理学措施将补充纵向设计，以进一步确定因果关系。此外，为了制定更有效的干预策略，以改善同时患有哮喘和精神健康问题的人的哮喘控制和精神健康，需要更多关于哮喘和精神健康随时间相互影响的程度以及这些关系的机制的信息。
