Department of Medicine, Schulich School of Medicine, University of Western Ontario, London, ON, Canada.
J Cutan Med Surg. 2012 Sep-Oct;16(5):300-5. doi: 10.1177/120347541201600505.
Psoriasis and vitiligo are both autoimmune diseases with an increased incidence noted in genetic relatives. They share similar trigger factors and have been observed to coexist in individuals.
The purpose was to review the literature on the coexistence of psoriasis and vitiligo and to determine if there is a higher than expected prevalence of psoriasis in patients with vitiligo and vice versa.
A literature review was conducted using Medline, EMBASE, and the Cochrane Library from 1968 to 2010. All articles that included reports of individuals with both psoriasis and vitiligo in the English language were documented.
We identified 338 articles, among which 35 case reports and 7 case series were mentioned. For each case series, the prevalence of psoriasis in patients with vitiligo, or vice versa, falls within the prevalence range of the background population on which the study was based.
An increase in the expected prevalence of psoriasis in individuals with vitiligo, or vice versa, was not found in our study, suggesting that the coexistence of the two diseases appears to be due to chance alone. Large epidemiologic studies are required to address with certainty whether psoriasis is more common in individuals with vitiligo and vice versa.
银屑病和白癜风都是自身免疫性疾病，在遗传亲属中发病率增加。它们有相似的诱发因素，并在个体中同时存在。
综述银屑病与白癜风共存的文献，并确定白癜风患者中银屑病的发病率是否高于预期，反之亦然。
从 1968 年至 2010 年，我们在 Medline、EMBASE 和 Cochrane 图书馆进行了文献回顾。所有包含银屑病和白癜风共存个体报告的英文文章都被记录下来。
我们确定了 338 篇文章，其中有 35 篇病例报告和 7 篇病例系列报道。对于每一个病例系列，白癜风患者中银屑病的发病率，或者反之，都在研究基础上的背景人群的发病率范围内。
我们的研究未发现白癜风患者中银屑病发病率增加，或者反之，这表明两种疾病的共存似乎只是偶然。需要进行大型的流行病学研究以确定白癜风患者中银屑病是否更常见，反之亦然。
