Lee Hemin, Lee Mu-Hyoung, Lee Dong Youn, Kang Hee Young, Kim Ki Ho, Choi Gwang Seong, Shin Jeonghyun, Lee Hee Jung, Kim Dong Hyun, Kim Tae Heung, Lee Ai-Young, Lee Seung Chul, Lee Sanghoon, Kim Kyoung Wan, Hann Seung-Kyung, Park Chul Jong, Oh Sang Ho
Department of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Department of Dermatology, Kyung Hee University School of Medicine, Seoul, Korea.
Yonsei Med J. 2015 May;56(3):719-25. doi: 10.3349/ymj.2015.56.3.719.
Vitiligo prevalence and its associated comorbidities rate have been reported variably among different populations. We aimed to determine the prevalence of vitiligo in Korea along with the baseline rate of comorbidities and compared the risks to the general population using hospital visit information of the total population in Korea.
We assessed demographic characteristics of vitiligo patients in Korean population from 2009 to 2011 in a nationwide data from Health Insurance Review Assessment Service. Patients who had at least one visit to Korea's primary, secondary, or tertiary referral hospitals with International Classification of Diseases, 10th Revision, Clinical Modification diagnosis code for vitiligo were identified. As a supplementary study, comorbidities associated with vitiligo were selected for further review to calculate relative risks compared to the general population.
The annual prevalence of vitiligo determined by hospital-visiting rate in Korea was 0.12% to 0.13% over a three year period. In sync with other previous epidemiological studies, there was bimodal distribution among the age groups and no difference between genders. Also, vitiligo in Korean population was associated with various autoimmune/non-autoimmune diseases such as thyroiditis, atopic dermatitis, and psoriasis.
This study was by far the most comprehensive review on prevalence of vitiligo using a data of total population in Korea. The prevalence is within a range of those reported in previous literatures, and increased risk of comorbidities such as thyroid diseases and psoriasis in vitiligo might aid clinicians in the initial work up of vitiligo patients and concurrent follow ups.
白癜风的患病率及其相关合并症发生率在不同人群中的报道各不相同。我们旨在确定韩国白癜风的患病率以及合并症的基线发生率，并利用韩国全体人口的医院就诊信息，将其风险与普通人群进行比较。
我们在健康保险审查评估服务中心的全国性数据中，评估了2009年至2011年韩国人群中白癜风患者的人口统计学特征。确定那些至少到韩国的一级、二级或三级转诊医院就诊过，且诊断代码符合《国际疾病分类》第10版临床修订本中白癜风诊断标准的患者。作为一项补充研究，我们选择了与白癜风相关的合并症进行进一步审查，以计算与普通人群相比的相对风险。
通过韩国医院就诊率确定的白癜风年患病率在三年期间为0.12%至0.13%。与之前的其他流行病学研究一致，年龄组之间存在双峰分布，性别之间无差异。此外，韩国人群中的白癜风与各种自身免疫性/非自身免疫性疾病相关，如甲状腺炎、特应性皮炎和银屑病。
本研究是迄今为止利用韩国全体人口数据对白癜风患病率进行的最全面的综述。该患病率在先前文献报道的范围内，白癜风患者中甲状腺疾病和银屑病等合并症风险的增加可能有助于临床医生对白癜风患者进行初步检查和同步随访。
