Shrestha S, Shrestha S, Shrestha L, Bhandary N
Department of Paediarics, Patan Hospital, Patan Academy of Health Sciences.
Kathmandu Univ Med J (KUMJ). 2012 Jan-Mar;10(37):40-3. doi: 10.3126/kumj.v10i1.6912.
Individuals residing at higher altitude may have oxygen saturation of hemoglobin different to those living at lower altitude.
To find out the baseline value of SpO2 in healthy Nepali children (2-14 years) living permanently at high altitude using pulse oximeter and also to study the relation of SpO2 with age, sex and ethnicity.
A descriptive observational study was conducted at 4 different altitudes ranging from 2700 to 3800 m in Mustang district. The mean pulse oximery values at different altitudes were calculated and compared.
One hundred six children were enrolled with the median age of 10 years. The mean SpO2 value of children permanently residing at altitude 2700m was 95.18%, at 2800m was 94.82%, at 3550m was 94.1% and 3800m was 93.1%.The difference in the SpO2 values at different altitude was statistically significant. No sex or age wise differences were noted on the mean SpO2 values in the study group.
The mean SpO2 values were higher than several other studies done in the altitude above 2500 meters. Enrollment of older children and the different ethnic background could be the contributing factors for the differences.
居住在高海拔地区的个体，其血红蛋白氧饱和度可能与低海拔地区居民不同。
使用脉搏血氧仪测定长期居住在高海拔地区的健康尼泊尔儿童（2至14岁）的SpO2基线值，并研究SpO2与年龄、性别和种族的关系。
在木斯塘地区海拔2700至3800米的4个不同高度进行了一项描述性观察研究。计算并比较了不同海拔高度的平均脉搏血氧饱和度值。
共纳入106名儿童，中位年龄为10岁。长期居住在海拔2700米处儿童的平均SpO2值为95.18%，2800米处为94.82%，3550米处为94.1%，3800米处为93.1%。不同海拔高度的SpO2值差异具有统计学意义。研究组中，平均SpO2值在性别和年龄方面均未观察到差异。
平均SpO2值高于其他在海拔2500米以上地区进行的多项研究。纳入年龄较大的儿童以及不同的种族背景可能是造成差异的因素。
