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Gender non-specific efficacy of ZFN mediated gene targeting in pigs.

作者信息

Hauschild-Quintern Janet, Petersen Bjoern, Queisser Anna-Lisa, Lucas-Hahn Andrea, Schwinzer Reinhard, Niemann Heiner

出版信息

Transgenic Res. 2013 Feb;22(1):1-3. doi: 10.1007/s11248-012-9647-6. Epub 2012 Sep 13.

DOI:10.1007/s11248-012-9647-6
PMID:22972477
Abstract
摘要

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本文引用的文献

1
B-cell depletion extends the survival of GTKO.hCD46Tg pig heart xenografts in baboons for up to 8 months.B 细胞耗竭可将 GTKO.hCD46Tg 猪心异种移植物在狒狒体内的存活时间延长至 8 个月以上。
Am J Transplant. 2012 Mar;12(3):763-71. doi: 10.1111/j.1600-6143.2011.03846.x. Epub 2011 Nov 9.
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Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases.利用锌指核酸酶高效生成二倍体敲除猪。
Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12013-7. doi: 10.1073/pnas.1106422108. Epub 2011 Jul 5.
3
Knockout rats via embryo microinjection of zinc-finger nucleases.
分子剪刀及其在转基因农场动物中的应用。
Transgenic Res. 2015 Jun;24(3):381-96. doi: 10.1007/s11248-015-9862-z. Epub 2015 Jan 22.
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Advances in genetic modification of farm animals using zinc-finger nucleases (ZFN).使用锌指核酸酶（ZFN）对农场动物进行基因改造的进展。
Chromosome Res. 2015 Feb;23(1):7-15. doi: 10.1007/s10577-014-9451-7.
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Progress and prospects for genetic modification of nonhuman primate models in biomedical research.生物医学研究中非人类灵长类动物模型基因改造的进展与前景。
ILAR J. 2013;54(2):211-23. doi: 10.1093/ilar/ilt035.
6
Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs.双等位基因CMP-唾液酸羟化酶基因敲除猪的培育
Sci Rep. 2013;3:1981. doi: 10.1038/srep01981.
通过胚胎显微注射锌指核酸酶制备基因敲除大鼠。
Science. 2009 Jul 24;325(5939):433. doi: 10.1126/science.1172447.
4
Production of alpha 1,3-galactosyltransferase gene-deficient pigs by somatic cell nuclear transfer: a novel selection method for gal alpha 1,3-Gal antigen-deficient cells.通过体细胞核移植生产α1,3-半乳糖基转移酶基因缺陷猪：一种针对半乳糖α1,3-半乳糖抗原缺陷细胞的新型筛选方法。
Mol Reprod Dev. 2008 Sep;75(9):1372-8. doi: 10.1002/mrd.20890.
5
Production of homozygous alpha-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer.通过育种和体细胞核移植生产纯合α-1,3-半乳糖基转移酶基因敲除猪。
Xenotransplantation. 2007 Jul;14(4):339-44. doi: 10.1111/j.1399-3089.2007.00417.x.
6
Swine generated by somatic cell nuclear transfer have increased incidence of intrauterine growth restriction (IUGR).通过体细胞核移植产生的猪出现宫内生长受限（IUGR）的发生率增加。
Cloning Stem Cells. 2007 Summer;9(2):229-36. doi: 10.1089/clo.2006.0079.
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Highly efficient endogenous human gene correction using designed zinc-finger nucleases.利用设计的锌指核酸酶进行高效的内源性人类基因校正。
Nature. 2005 Jun 2;435(7042):646-51. doi: 10.1038/nature03556. Epub 2005 Apr 3.
8
Establishment of male and female nuclear transfer embryonic stem cell lines from different mouse strains and tissues.从不同小鼠品系和组织建立雄性和雌性核移植胚胎干细胞系。
Biol Reprod. 2005 Apr;72(4):932-6. doi: 10.1095/biolreprod.104.035105. Epub 2004 Dec 15.
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Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases.利用锌指核酸酶在果蝇中进行靶向染色体切割和诱变。
Genetics. 2002 Jul;161(3):1169-75. doi: 10.1093/genetics/161.3.1169.
10
Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs.克隆猪中α1,3-半乳糖基转移酶基因的靶向破坏。
Nat Biotechnol. 2002 Mar;20(3):251-5. doi: 10.1038/nbt0302-251.