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不同超高场 B₁ mapping 技术的理论与实验比较。

A theoretical and experimental comparison of different techniques for B₁ mapping at very high fields.

机构信息

Max Planck Institute for Biological Cybernetics, Magnetic Resonance Center, Tübingen, Germany.

出版信息

NMR Biomed. 2013 Mar;26(3):265-75. doi: 10.1002/nbm.2844. Epub 2012 Sep 13.

Abstract

With the increasing use of ultrahigh-field MR with multiple transmit channels, mapping of the B₁(+) field has become a critical factor in many studies, leading to the publication of a large number of sequences for the measurement of the flip angle in recent years. In this article, the accuracy, precision and practicability of some of the most prominent of these techniques are investigated both theoretically, using error propagation computations and Monte-Carlo simulations, and experimentally for different settings. For an exemplary experiment, which is typical for high-field applications, the flip angle uncertainty is calculated and measured for two- and three-dimensional acquisitions for techniques based on both magnitude and phase data. Simulated and measured results show good agreement. An experimental assessment of T₁ and B₀ dependence yields weak variations with these parameters for only a few of the sequences. Measurements on human scanners show crucial influences of specific absorption rate limitations, especially at ultrahigh field.

摘要

随着多通道超高场磁共振的应用越来越广泛,B₁(+)场的映射已成为许多研究的关键因素,近年来发布了大量用于测量翻转角的序列。本文从理论上(使用误差传播计算和蒙特卡罗模拟)和实验上(针对不同的设置)研究了其中一些最突出的技术的准确性、精密度和实用性。对于一个典型的高场应用示例实验,针对基于幅度和相位数据的两种和三维采集技术,计算和测量了翻转角不确定性。模拟和测量结果吻合较好。对 T₁和 B₀依赖性的实验评估表明,只有少数几个序列随这些参数有微弱变化。人体扫描仪上的测量结果表明,吸收率限制的特定影响至关重要,尤其是在超高场。

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