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基于深度学习的7T全脑B值映射

Deep learning-based whole-brain B -mapping at 7T.

作者信息

Krueger Felix, Aigner Christoph Stefan, Lutz Max, Riemann Layla Tabea, Degenhardt Katja, Hadjikiriakos Kimon, Zimmermann Felix Frederik, Hammernik Kerstin, Schulz-Menger Jeanette, Schaeffter Tobias, Schmitter Sebastian

机构信息

Physikalisch-Technische Bundesanstalt, Berlin, Germany.

Einstein Centre Digital Future, Technische Universität Berlin, Biomedical Engineering, Berlin, Germany.

出版信息

Magn Reson Med. 2025 Apr;93(4):1700-1711. doi: 10.1002/mrm.30359. Epub 2024 Oct 27.

DOI:10.1002/mrm.30359
PMID:39462473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11782730/
Abstract

PURPOSE

This study investigates the feasibility of using complex-valued neural networks (NNs) to estimate quantitative transmit magnetic RF field (B ) maps from multi-slice localizer scans with different slice orientations in the human head at 7T, aiming to accelerate subject-specific B -calibration using parallel transmission (pTx).

METHODS

Datasets containing channel-wise B -maps and corresponding multi-slice localizers were acquired in axial, sagittal, and coronal orientation in 15 healthy subjects utilizing an eight-channel pTx transceiver head coil. Training included five-fold cross-validation for four network configurations: used transversal, sagittal, coronal data, and was trained on all slice orientations. The resulting maps were compared to B -reference scans using different quality metrics. The proposed network was applied in-vivo at 7T in two unseen test subjects using dynamic kt-point pulses.

RESULTS

Predicted B -maps demonstrated a high similarity with measured B -maps across multiple orientations. The estimation matched the reference with a mean relative error in the magnitude of (2.70 ± 2.86)% and mean absolute phase difference of (6.70 ± 1.99)° for transversal, (1.82 ± 0.69)% and (4.25 ± 1.62)° for sagittal ( ), as well as (1.33 ± 0.27)% and (2.66 ± 0.60)° for coronal slices ( ) considering brain tissue. trained on all orientations enables a robust prediction of B -maps across different orientations. Achieving a homogenous excitation over the whole brain for an in-vivo application displayed the approach's feasibility.

CONCLUSION

This study demonstrates the feasibility of utilizing complex-valued NNs to estimate multi-slice B -maps in different slice orientations from localizer scans in the human brain at 7T.

摘要

目的

本研究探讨使用复值神经网络(NNs)从7T人体头部不同切片方向的多层定位扫描中估计定量发射磁射频场(B)图的可行性,旨在利用并行传输(pTx)加速特定受试者的B校准。

方法

使用八通道pTx收发器头部线圈,在15名健康受试者中获取包含逐通道B图和相应多层定位器的数据集,扫描方向为轴向、矢状和冠状。训练包括对四种网络配置进行五折交叉验证:使用横向、矢状、冠状数据,以及在所有切片方向上进行训练。使用不同的质量指标将所得图与B参考扫描进行比较。所提出的网络在7T下对两名未见过的测试受试者进行体内应用,使用动态kt点脉冲。

结果

预测的B图在多个方向上与测量的B图显示出高度相似性。对于横向切片,估计值与参考值匹配,幅度的平均相对误差为(2.70±2.86)%,平均绝对相位差为(6.70±1.99)°;对于矢状切片(),分别为(1.82±0.69)%和(4.25±1.62)°;对于冠状切片(),考虑脑组织时分别为(1.33±0.27)%和(2.66±0.60)°。在所有方向上进行训练的能够对不同方向的B图进行稳健预测。在体内应用中实现全脑均匀激发显示了该方法的可行性。

结论

本研究证明了利用复值神经网络从7T人脑定位扫描中估计不同切片方向的多层B图的可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/d1bd11528489/MRM-93-1700-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/befa752c61ed/MRM-93-1700-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/469c984e6292/MRM-93-1700-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/7b0c1da3c362/MRM-93-1700-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/e42ffe09152a/MRM-93-1700-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/d1bd11528489/MRM-93-1700-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/befa752c61ed/MRM-93-1700-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/469c984e6292/MRM-93-1700-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/7b0c1da3c362/MRM-93-1700-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/e42ffe09152a/MRM-93-1700-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/876e/11782730/d1bd11528489/MRM-93-1700-g005.jpg

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本文引用的文献

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Joint [Formula: see text] and Image Reconstruction in Low-Field MRI by Physics-Informed Deep-Learning.基于物理信息深度学习的低场 MRI 中的关节[公式:见正文]与图像重建。
IEEE Trans Biomed Eng. 2024 Oct;71(10):2842-2853. doi: 10.1109/TBME.2024.3396223. Epub 2024 Sep 19.
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Unsupervised deep learning with convolutional neural networks for static parallel transmit design: A retrospective study.基于卷积神经网络的无监督深度学习在静态并行发射设计中的应用:一项回顾性研究。
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Deep learning-based local SAR prediction using B maps and structural MRI of the head for parallel transmission at 7 T.
基于深度学习的头部 B 图和结构 MRI 的局部 SAR 预测,用于 7T 并行传输。
Magn Reson Med. 2023 Dec;90(6):2524-2538. doi: 10.1002/mrm.29797. Epub 2023 Jul 19.
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Rapid 3D absolute B mapping using a sandwiched train presaturated TurboFLASH sequence at 7 T for the brain and heart.在 7T 磁共振扫描仪上使用夹心式预饱和 TurboFLASH 序列进行快速 3D 全脑和全心绝对 B 映射。
Magn Reson Med. 2023 Mar;89(3):964-976. doi: 10.1002/mrm.29497. Epub 2022 Nov 6.
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Magn Reson Med. 2023 Mar;89(3):1002-1015. doi: 10.1002/mrm.29510. Epub 2022 Nov 6.
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Optimized ultrahigh field parallel transmission workflow using rapid presaturated TurboFLASH transmit field mapping with a three-dimensional centric single-shot readout.采用三维中心单次激发读取的快速预饱和 TurboFLASH 传输场映射进行优化的超高场并行传输工作流程。
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