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携带 pKPN101-IT 的耐多药肺炎克雷伯菌 ST101 株的抗菌治疗和控制措施，该质粒为新型完全测序 bla(KPC-2) 质粒。

Antimicrobial treatment and containment measures for an extremely drug-resistant Klebsiella pneumoniae ST101 isolate carrying pKPN101-IT, a novel fully sequenced bla(KPC-2) plasmid.

机构信息

Department of Molecular Medicine, Padua, Italy.

出版信息

J Clin Microbiol. 2012 Nov;50(11):3768-72. doi: 10.1128/JCM.01892-12. Epub 2012 Sep 12.

DOI:10.1128/JCM.01892-12
PMID:22972824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3486238/
Abstract

An extremely drug-resistant Klebsiella pneumoniae isolate, sequence type ST101, was isolated from a patient in Italy. We describe antibiotic treatment, measures to clear and contain the infection, and a complete sequence analysis of a novel large plasmid, pKPN101-IT, harboring the bla(KPC-2) gene and arising from the threatening recombination of different worldwide-distributed backbones.

摘要

一株来自意大利患者的超耐药肺炎克雷伯菌分离株，序列型 ST101，被分离出来。我们描述了抗生素治疗、清除和控制感染的措施，以及一个新型大质粒 pKPN101-IT 的完整序列分析，该质粒携带 bla(KPC-2) 基因，源于不同分布于世界各地的骨架之间的威胁性重组。

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Antimicrobial treatment and containment measures for an extremely drug-resistant Klebsiella pneumoniae ST101 isolate carrying pKPN101-IT, a novel fully sequenced bla(KPC-2) plasmid.携带 pKPN101-IT 的耐多药肺炎克雷伯菌 ST101 株的抗菌治疗和控制措施，该质粒为新型完全测序 bla(KPC-2) 质粒。
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