Karahmadi Mojgan, Layegh Elmira, Layegh Samira, Keypour Maryam
Assistant Professor, Department of Psychiatry, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
J Res Med Sci. 2011 Oct;16(10):1378-81.
Anorexia nervosa (AN) is a difficult-to-treat psychosomatic disease. Very few cases of acute liver failure associated with AN have been described. We describe one patient who was affected by AN and presented high level increase of serum liver enzymes, along with sever thrombocytopenia. Then, we discuss the possible etiopathogenic factors.
A 14-year-old boy with AN was admitted in the pediatric psychiatric emergency department of Alzahra Hospital with impaired electrolyte levels, bradycardia, hypotension, liver dysfunction, and thrombocytopenia.
A ten-time increase in liver enzymes and thrombocytopenia were observed on admission. After two months of treatment, the levels were within the normal range.
Improvement of initial clinical symptoms and recovery of liver enzymes and thrombocytopenia after the treatment suggested that liver dysfunction and thrombocytopenia may be observed in AN patients and should be taken care of by physicians.
神经性厌食症（AN）是一种难以治疗的心身疾病。与AN相关的急性肝衰竭病例报道极少。我们描述了一名患有AN的患者，其血清肝酶水平大幅升高，同时伴有严重血小板减少症。然后，我们讨论了可能的病因学因素。
一名14岁患有AN的男孩因电解质水平受损、心动过缓、低血压、肝功能障碍和血小板减少症入住阿尔扎赫拉医院儿科精神科急诊科。
入院时观察到肝酶升高了10倍且伴有血小板减少症。经过两个月的治疗，各项指标恢复到正常范围。
治疗后初始临床症状改善，肝酶和血小板减少症恢复，提示AN患者可能出现肝功能障碍和血小板减少症，医生应予以关注。
