Jersey Shore University Medical Center, Neptune, New Jersey, USA.
J Natl Med Assoc. 2012 May-Jun;104(5-6):265-73. doi: 10.1016/s0027-9684(15)30158-9.
It is well documented that African American populations are disproportionately affected by type 2 diabetes mellitus compared with their white counterparts. They have a higher prevalence of diabetes, a higher rate of diabetes-related complications, greater disability from these complications, and poorer control and quality of care. In order to improve diabetes care and outcomes in African Americans (and indeed all patients with diabetes), a multifactorial approach is needed to target all risk factors-not solely hyperglycemia-simultaneously. Culturally appropriate initiatives to improve lifestyle behaviors are a first step in management. Community-based programs, including those mediated through church groups, have reported varying degrees of success in effecting such beneficial lifestyle changes. If these measures fail to achieve desirable levels of blood glucose, blood pressure, and serum lipids, pharmacologic therapy is indicated. However, few evidence-based recommendations regarding the use of some drugs in African Americans currently exist due to their underrepresentation in randomized controlled clinical trials. Other essential components of diabetes care include regular screening for diabetic nephropathy and neuropathy, and eye and foot examinations, with prompt referral to specialists when important clinical changes are detected.
有大量文献记载表明,与白种人相比,非裔美国人 2 型糖尿病的发病率不成比例地更高。他们患糖尿病的概率更高,糖尿病相关并发症的发生率更高,这些并发症导致的残疾程度更大,并且他们的血糖控制和护理质量更差。为了改善非裔美国人(实际上是所有糖尿病患者)的糖尿病护理和预后,需要采取多因素方法来同时针对所有风险因素——而不仅仅是高血糖。改善生活方式行为的文化适宜性举措是管理的第一步。基于社区的计划,包括通过教会团体进行的计划,已经报告在实现这种有益的生活方式改变方面取得了不同程度的成功。如果这些措施未能达到理想的血糖、血压和血清脂质水平,则需要药物治疗。然而,由于在随机对照临床试验中代表性不足,目前关于某些药物在非裔美国人中使用的建议很少有循证依据。糖尿病护理的其他重要组成部分包括定期筛查糖尿病肾病和神经病变,以及眼部和足部检查,一旦发现重要的临床变化,应及时转介给专家。