Department of Clinical Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh city, Ho Chi Minh city, Vietnam Department of Pharmacotherapy and Pharmaceutical Care, University of Groningen, Groningen, the Netherlands Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico Department of Clinical Pharmacology, University Medical Center Groningen, Groningen, the Netherlands.
Trop Med Int Health. 2012 Dec;17(12):1552-66. doi: 10.1111/j.1365-3156.2012.03081.x. Epub 2012 Sep 14.
To identify indicators of quality use of medicines used in South-East Asian region.
A systematic review was conducted searching MEDLINE, Embase and The International Network for Rational Use of Drugs (INRUD) and The World Health Organization (WHO) website. Original studies or reports carried out in the South-East Asian region, explicitly using indicators to measure quality use of medicines, and published between January 2000 and July 2011 were included.
A total of 17 studies conducted in 7 of 11 countries in South-East Asia were included. WHO indicators focusing on general medication use in health facilities were most widely used (10 studies). Twelve studies used non-WHO indicators for measuring quality use of medicines in clinical areas (geriatrics and obstetrics) or specific diseases, such as diarrhoea and pneumonia. In five studies, WHO indicators were used along with non-WHO indicators. There was little information available about validity, reliability and feasibility of the non-WHO indicators. The majority of indicators measured process rather than structure or outcome. There were very few indicators addressing non-communicable diseases.
A limited number of studies have been published explicitly using indicators of quality use of medicines across South-East Asia. Importantly, existing indicators need to be complemented with valid, reliable and feasible indicators related to non-communicable diseases, particularly those with a high financial burden to meet the current medical challenges in the region.
确定东南亚地区使用的药品质量使用的指标。
系统检索 MEDLINE、Embase 和国际合理用药网络（INRUD）以及世界卫生组织（WHO）网站，纳入 2000 年 1 月至 2011 年 7 月期间在东南亚地区进行的、明确使用指标来衡量药品质量使用的原始研究或报告。
共纳入 11 个东南亚国家中的 7 个国家的 17 项研究。使用最广泛的是针对卫生机构一般药物使用的世卫组织指标（10 项研究）。12 项研究在临床领域（老年病学和妇产科）或特定疾病（如腹泻和肺炎）中使用非世卫组织指标来衡量药品质量使用。在五项研究中，同时使用了世卫组织和非世卫组织的指标。关于非世卫组织指标的有效性、可靠性和可行性的信息很少。大多数指标衡量的是过程而不是结构或结果。几乎没有指标涉及非传染性疾病。
在整个东南亚地区，明确使用药品质量使用指标的研究数量有限。重要的是，需要用有效、可靠和可行的非传染性疾病指标来补充现有的指标，特别是那些对满足该地区当前医疗挑战具有高财务负担的指标。
