Pretagostini R, Ricci A, Gabbrielli F, Lai Q, Stabile D, Puoti F, Fiaschetti P, Oliveti A, Peritore D, Rizzato L, Nanni C A
Interregional Centre Organizzazione Centro-Sud Trapianti, Surgery Sciences Department of Policlinico of Rome Umberto I, Rome, Italy.
Transplant Proc. 2012 Sep;44(7):1818-9. doi: 10.1016/j.transproceed.2012.06.050.
Validity of living donor kidney transplantation is universally accepted. In contrast, after enthusiastic adoption in the 1990s, living donor liver transplantation has decreased in recent years. The aim of the present study was to evaluate retrospectively the current use of this form of donation in Italy by comparing liver and kidney cadaveric and living donations from 2002 to 2010. The number of liver transplantations from living donors has decreased from 34 in 2002 (3.9% of total) to 13 in 2010 (1.3% of total). In contrast, kidney transplantation from living donors increased from 126 (7.9% of total) to 186 (11% of total). We observed that living donations for kidney transplantation are still underused, especially with unrelated donors. Living donor liver transplantation has decreased in recent years; this procedure should be reserved to centers with particular expertise. It would be appropriate to implement programs to increase the attention of health professionals and the general population and to integrate living donations into programs of deceased organ donation.
活体供肾移植的有效性已得到普遍认可。相比之下，20世纪90年代得到广泛应用后，近年来活体供肝移植数量有所减少。本研究的目的是通过比较2002年至2010年肝脏和肾脏的尸体及活体捐赠情况，对意大利目前这种捐赠形式的使用情况进行回顾性评估。活体供肝移植的数量从2002年的34例（占总数的3.9%）降至2010年的13例（占总数的1.3%）。相比之下，活体供肾移植从126例（占总数的7.9%）增加到186例（占总数的11%）。我们观察到，用于肾移植的活体捐赠仍未得到充分利用，尤其是非亲属捐赠者。近年来活体供肝移植数量减少；该手术应保留给具有特殊专业知识的中心。实施相关项目以提高卫生专业人员和普通民众的关注度，并将活体捐赠纳入死者器官捐赠项目是合适的。
