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肾上腺神经节细胞瘤:一例报告

Adrenal Ganglioneuroma: A Case Report.

作者信息

Aynaou Hayat, Salhi Houda, El Ouahabi Hanan

机构信息

Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital, Fes, MAR.

出版信息

Cureus. 2022 Aug 3;14(8):e27634. doi: 10.7759/cureus.27634. eCollection 2022 Aug.

Abstract

Adrenal ganglioneuroma (AGN) are sympathetic differentiated tumors that originate from neural crest cells. It is a rare benign tumor in children and young adults. These lesions are usually asymptomatic and tend to be hormonally silent. Their discovery is fortuitous in imaging examinations. Preoperative diagnosis remains difficult, and the gold standard treatment is adrenalectomy. There is a good prognosis after surgery without recurrence. We herein report a case of adrenal ganglioneuroma in a 40-year-old man who benefited from an abdominal CT scan in the face of a complaint of abdominal discomfort and as part of the extension assessment of his colonic adenocarcinoma. Abdominal CT scan with contrast showed a left retroperitoneal mass of triangular shape within the adrenal lodge of tissue density, containing some calcifications not enhanced after injection of contrast product, measuring 90 x 62 mm in diameter (AP x T) with a relative washout calculated at 30%. Biopsy and histological examination of the mass suggested an adrenal ganglioneuroma.

摘要

肾上腺节细胞神经瘤(AGN)是起源于神经嵴细胞的交感神经分化肿瘤。它是儿童和年轻人中罕见的良性肿瘤。这些病变通常无症状,且往往无激素活性。它们在影像学检查中偶然被发现。术前诊断仍然困难,金标准治疗方法是肾上腺切除术。术后预后良好,无复发。我们在此报告一例40岁男性肾上腺节细胞神经瘤病例,该患者因腹部不适就诊,作为其结肠腺癌扩展评估的一部分接受了腹部CT扫描。增强腹部CT扫描显示左肾上腺区有一个三角形的腹膜后肿块,呈组织密度,含有一些钙化,注射造影剂后无强化,直径为90×62mm(前后径×上下径),相对廓清率计算为30%。对该肿块进行活检和组织学检查提示为肾上腺节细胞神经瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2159/9438294/d894861d77ed/cureus-0014-00000027634-i01.jpg

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