Lau Su Yin, Yong Tuck Yean
Department of Gastroenterology, Flinders Medical Centre, Australia.
Intern Med. 2012;51(17):2371-4. doi: 10.2169/internalmedicine.51.7879. Epub 2012 Sep 1.
Patients with acute adrenal insufficiency may have musculoskeletal symptoms including flexion contractures, myopathy and hyperkalaemic neuromyopathy. However, the association between rhabdomyolysis and acute adrenal insufficiency is extremely rare and has only been reported infrequently in the literature. Hyponatraemia is often present in association with acute adrenal insufficiency complicated by rhabdomyolysis. We herein report the case of a patient with acute primary adrenal insufficiency and severe hyponatraemia complicated by rhabdomyolysis and acute kidney injury.
急性肾上腺功能不全患者可能出现肌肉骨骼症状,包括屈曲挛缩、肌病和高钾性神经肌病。然而,横纹肌溶解与急性肾上腺功能不全之间的关联极为罕见,文献中仅有少量报道。低钠血症常与并发横纹肌溶解的急性肾上腺功能不全相关。我们在此报告一例急性原发性肾上腺功能不全并伴有严重低钠血症、并发横纹肌溶解和急性肾损伤的患者。