艾迪生病中的肌病
Myopathy in Addison's disease.
作者信息
Mor F, Green P, Wysenbeek A J
出版信息
Ann Rheum Dis. 1987 Jan;46(1):81-3. doi: 10.1136/ard.46.1.81.
Abstract
Since the first description of primary adrenocortical insufficiency by Thomas Addison in 1855 several large series of patients with Addison's disease have been published. The common signs and symptoms include: weakness, hyperpigmentation, weight loss, gastrointestinal complaints, and hypotension. It is rare for patients with Addison's disease to present with musculoskeletal symptoms including flexion contractures, hyperkalaemic neuromyopathy, Guillain-Barré syndrome, migratory myalgia, sciatica-like pain, and low back pain. Myopathy has not been previously described in Addison's disease. Herein we report a patient presenting with severe hyponatraemia and myopathy which resolved after steroid replacement therapy.
摘要
自1855年托马斯·艾迪生首次描述原发性肾上腺皮质功能不全以来，已发表了几篇关于艾迪生病患者的大型系列报道。常见的体征和症状包括：虚弱、色素沉着、体重减轻、胃肠道不适和低血压。艾迪生病患者出现肌肉骨骼症状，如屈曲挛缩、高钾性神经病变、吉兰-巴雷综合征、游走性肌痛、坐骨神经痛样疼痛和腰痛的情况较为罕见。此前尚未有艾迪生病伴发肌病的相关描述。在此，我们报告一例出现严重低钠血症和肌病的患者，其在接受类固醇替代治疗后症状得到缓解。
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