Nishino Takuma, Koneri Kenji, Nagano Hideki, Murakami Makoto, Hirono Yasuo, Goi Takanori, Iida Atsushi, Katayama Kanji, Ito Hiroshi, Yamaguchi Akio
1st Department of Surgery, University of Fukui.
Nihon Shokakibyo Gakkai Zasshi. 2012 Sep;109(9):1575-83.
A 69-year-old man was admitted to our hospital with epigastric discomfort. Upper gastrointestinal endoscopy showed a submucosal tumor near the papilla of Vater. Abdominal CT and MRI showed a small, well-enhanced tumor. Endoscopic tumor biopsy was performed before the operation, but pathologic findings showed normal duodenal musosa. Nevertheless, since malignancy could not be ruled out, we resected the tumor with the sphincter of the papilla of Vater, followed by plasty of the orifice for the common bile duct and main pancreatic duct. We identified 3 parts with tumor cells; epithelioid cells, spindle cells, and ganglion-like cells. The tumor was diagnosed as gangliocytic paraganglioma of the duodenum. Treatment by resecting the tumor with the sphincter of the papilla of Vater, followed by the plasty of the orifice for the common bile duct and main pancreatic duct, was selected considering the patient's safety and to achieve radical cure.
一名69岁男性因上腹部不适入院。上消化道内镜检查显示在十二指肠乳头附近有一个黏膜下肿瘤。腹部CT和MRI显示为一个小的、强化良好的肿瘤。术前进行了内镜肿瘤活检,但病理结果显示十二指肠黏膜正常。然而,由于不能排除恶性肿瘤,我们切除了带有十二指肠乳头括约肌的肿瘤,随后对胆总管和主胰管开口进行了成形术。我们发现肿瘤细胞有3种成分;上皮样细胞、梭形细胞和神经节样细胞。该肿瘤被诊断为十二指肠神经节细胞性副神经节瘤。考虑到患者的安全并实现根治,选择了切除带有十二指肠乳头括约肌的肿瘤,随后对胆总管和主胰管开口进行成形术的治疗方法。