Yesilada Aysin Karasoy, Sevim Kamuran Zeynep, Sirvan Selami Serhat, Irmak Fatih, Tatlidede Hamit Soner
Department of Plastic and Reconstructive Surgery, Sisli Etfal Research and Training Hospital, Istanbul, Turkey.
J Craniofac Surg. 2012 Sep;23(5):e461-3. doi: 10.1097/SCS.0b013e31825b33c2.
Acquired partial lipodystrophy is a rare disorder, and it is characterized by the absence of subcutaneous fat from the face, the neck, the trunk, and the upper extremities. The etiology of acquired partial lipodystrophy includes scleroderma and discoid lupus erythematosus. Literature review reveals studies involving 10 patients until today with lipoatrophy due to or after the onset of discoid lupus erythematosus; all are female patients. We want to report a young male patient with progressive symmetrical facial lipoatrophy. In addition, he has discoid lupus erythematosus and celiac disease. Fat grafting and adjuvant oral coenzyme Q10 tablets (Deka-none; Deka Pharmaceuticals, İstanbul, Turkey) were administered for treatment. To our knowledge, this case involves the first male patient in the literature presenting with symmetrical facial lipoatrophy with very prominent periorbital lipoatrophy and bitemporal hollowing symptoms.
获得性部分脂肪营养不良是一种罕见的疾病，其特征是面部、颈部、躯干和上肢缺乏皮下脂肪。获得性部分脂肪营养不良的病因包括硬皮病和盘状红斑狼疮。文献综述显示，迄今为止有涉及10例因盘状红斑狼疮发病或发病后出现脂肪萎缩的研究；所有患者均为女性。我们想报告一位患有进行性对称性面部脂肪萎缩的年轻男性患者。此外，他还患有盘状红斑狼疮和乳糜泻。采用脂肪移植和辅助口服辅酶Q10片（Deka-none；土耳其伊斯坦布尔Deka制药公司）进行治疗。据我们所知，该病例是文献中首例出现对称性面部脂肪萎缩且伴有非常明显的眶周脂肪萎缩和双侧颞部凹陷症状的男性患者。
