Division of Otolaryngology - Head & Neck Surgery, Dalhousie University, Halifax, NS, Canada.
J Otolaryngol Head Neck Surg. 2019 Nov 14;48(1):63. doi: 10.1186/s40463-019-0382-3.
Facial lipoatrophy is a rare condition described by the disappearance of facial subcutaneous fat. The etiology of lipoatrophy can be congenital, or acquired including traumatic, iatrogenic or idiopathic. Idiopathic facial lipoatrophy has only been previously identified in three case reports, among which, the patient demographics vary considerably. Two of these case reports have identified a role for autologous fat transfer as a means of treatment. This case differs from those in the literature in patient demographics and severity of the facial lipoatrophy. The aim of the current report is to present a rare case of idiopathic facial lipoatrophy, and to assess the use of autologous fat transfer as a treatment modality.
We present a case of a 40-year old woman from Nova Scotia, Canada who presented with asymptomatic idiopathic facial lipoatrophy. The patient was otherwise healthy, taking no medications with no trauma or surgery in the region affected. Investigations, including a full autoimmune workup, were unremarkable. The facial lipoatrophy was considerably disfiguring and was assessed as a Grade 4 on the facial lipoatrophy scale. The patient was treated over the course of 2 years with two autologous fat transfers.
Achieving resolution of idiopathic lipoatrophy is important to patients because it can manifest in a disfiguring form and have negative effects on quality of life. The current study reports a treatment of idiopathic lipoatrophy that achieved results acceptable to the patient.
面部脂肪萎缩是一种罕见的病症,表现为面部皮下脂肪消失。脂肪萎缩的病因可以是先天性的,也可以是后天获得的,包括创伤性的、医源性的或特发性的。特发性面部脂肪萎缩此前仅在三例病例报告中被发现,其中患者的人口统计学特征差异很大。其中两份病例报告确定了自体脂肪移植作为一种治疗方法的作用。本病例与文献中的病例在患者人口统计学特征和面部脂肪萎缩的严重程度上有所不同。本报告的目的是介绍一例罕见的特发性面部脂肪萎缩病例,并评估自体脂肪移植作为一种治疗方法的效果。
我们报告了一例来自加拿大新斯科舍省的 40 岁女性患者,她患有无症状的特发性面部脂肪萎缩。患者身体健康,无该区域外伤或手术史,也未服用任何药物。包括全面自身免疫检查在内的各项检查均无异常。面部脂肪萎缩严重影响美观,根据面部脂肪萎缩量表评估为 4 级。患者接受了两年两次的自体脂肪移植治疗。
特发性脂肪萎缩的治疗对于患者非常重要,因为它可能以畸形的形式出现,并对生活质量产生负面影响。本研究报告了一例特发性脂肪萎缩的治疗方法,其结果令患者满意。