一名塞扎里综合征患者的细胞遗传学研究。

Cytogenetic study of a patient with the Sézary syndrome.

作者信息

Solé F, Tarrida N, Coll M D, Caballin M R, De Miguel A, Woessner S, Egozcue J

机构信息

Departament de Biologia Cellular i Fisiologia, Facultat de Ciències, Universitat Autònoma de Barcelona, Spain.

出版信息

Cancer Genet Cytogenet. 1990 Feb;44(2):193-6. doi: 10.1016/0165-4608(90)90046-d.

DOI:10.1016/0165-4608(90)90046-d

PMID:2297678

Abstract

A cytogenetic study was performed in a patient with Sézary syndrome, which is a T-helper lymphoproliferative disorder. Metaphases were obtained from a phytohemagglutinin-stimulated lymphocyte culture. Normal, hypodiploid (42 to 45 chromosomes) and hypotetraploid (84 to 88 chromosomes) cells were observed. Both abnormal cell lines showed the same abnormalities involving chromosomes 1, 2, 4, 6, 10, 11, 12, 14, 16, and 20.

摘要

对一名患有蕈样肉芽肿综合征（一种T辅助淋巴细胞增殖性疾病）的患者进行了细胞遗传学研究。中期细胞是从经植物血凝素刺激的淋巴细胞培养物中获得的。观察到正常、亚二倍体（42至45条染色体）和亚四倍体（84至88条染色体）细胞。两种异常细胞系均显示出涉及1、2、4、6、10、11、12、14、16和20号染色体的相同异常。