一例Sezary综合征的细胞遗传学发现
Cytogenetic findings in a case of Sézary syndrome.
作者信息
Schmidt M, Stolzmann W M, Neumann E
出版信息
Cancer Genet Cytogenet. 1985 Mar 15;16(2):117-21. doi: 10.1016/0165-4608(85)90004-4.
PMID:3971337
Abstract
Repeated cytogenetic studies were carried out on a Sézary syndrome patient during a 1-year period. The presence of a single clone of heteroploid (60-86 chromosomes) cells was a permanent finding in the PHA-stimulated blood cultures. The bone marrow was normal. Sister chromatid exchange (SCE) value was relatively lower in heteroploid cells.
摘要
在1年的时间里，对一名 Sézary 综合征患者进行了多次细胞遗传学研究。在PHA刺激的血液培养物中，始终发现存在一个异倍体（60 - 86条染色体）细胞克隆。骨髓正常。异倍体细胞中的姐妹染色单体交换（SCE）值相对较低。
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