Giannitti Federico, Margineda Carlos A, Cid María S, Diab Santiago S, Weber Natalia, Rodríguez Alejandro, Campero Carlos M, Odriozola Ernesto R
California Animal Health and Food Safety Laboratory System, University of California, Davis, CA, USA.
J Vet Diagn Invest. 2012 Nov;24(6):1068-72. doi: 10.1177/1040638712458784. Epub 2012 Sep 13.
The current study describes a naturally occurring cluster of cases of Wedelia glauca intoxication. Seven of 14 axis deer (Axis axis) and 1 of 8 llamas (Lama glama) in a zoo of Buenos Aires province, Argentina, died suddenly after ingestion of a new batch of alfalfa (Medicago sativa) hay bales contaminated with the hepatotoxic plant W. glauca. Necropsies of 1 deer and 1 llama were performed. Pathological findings in both animals included severe diffuse acute centrilobular hepatocellular necrosis and hemorrhage, and clear yellowish translucent gelatinous edema on the wall of the gall bladder and the serosa of the choledochoduodenal junction. Fragments of W. glauca plants were identified in the hay based on the botanical characteristics of the leaves. Samples of gastric contents were examined by microhistological analysis, which identified epidermal fragments of W. glauca based on the presence of characteristic uniseriate glandular hairs (trichomes), confirming recent ingestion of W. glauca in both cases. The fragments were quantified and represented 5% of all examined vegetal fragments in the deer and 10% in the llama.
本研究描述了一起自然发生的南美蟛蜞菊中毒病例群。在阿根廷布宜诺斯艾利斯省的一个动物园里，14只泽鹿（Axis axis）中有7只，8只美洲驼（Lama glama）中有1只，在摄入一批被具有肝毒性的植物南美蟛蜞菊（Wedelia glauca）污染的新苜蓿（Medicago sativa）干草捆后突然死亡。对1只鹿和1只美洲驼进行了尸检。两只动物的病理检查结果均包括严重的弥漫性急性小叶中心肝细胞坏死和出血，以及胆囊壁和胆总管十二指肠交界处浆膜上明显的淡黄色半透明胶冻样水肿。根据叶子的植物学特征，在干草中鉴定出了南美蟛蜞菊的碎片。通过显微组织学分析对胃内容物样本进行检查，根据特征性单列腺毛（表皮毛）的存在鉴定出南美蟛蜞菊的表皮碎片，证实这两只动物近期均摄入了南美蟛蜞菊。对这些碎片进行了定量，在鹿的所有检查植物碎片中占5%，在美洲驼中占10%。
