• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

副蛋白血症性角膜浸润的不寻常表现。

Unusual presentation of paraproteinemic corneal infiltrates.

作者信息

Spiegel P, Grossniklaus H E, Reinhart W J, Thomas R H

机构信息

Department of Pathology, University Hospitals of Cleveland, Case Western Reserve University, Ohio.

出版信息

Cornea. 1990 Jan;9(1):81-5.

PMID:2298000
Abstract

A 76-year-old man with bilateral corneal infiltrates secondary to a monoclonal gammopathy of undetermined significance (MGUS) is described. The corneal changes simulated a remote lattice dystrophy. Although the clinical presentation of corneal opacities secondary to paraproteinemic conditions is somewhat variable, this patient's corneas lacked the common crystalline appearance of immunoglobulin deposits. This patient demonstrates an atypical clinical presentation of corneal infiltration secondary to a paraproteinemia.

摘要

本文描述了一名76岁男性,患有意义未明的单克隆丙种球蛋白病(MGUS)继发双侧角膜浸润。角膜改变类似陈旧性格子状营养不良。尽管副蛋白血症相关角膜混浊的临床表现有所不同,但该患者的角膜缺乏免疫球蛋白沉积常见的结晶外观。该患者表现出副蛋白血症继发角膜浸润的非典型临床表现。

相似文献

1
Unusual presentation of paraproteinemic corneal infiltrates.副蛋白血症性角膜浸润的不寻常表现。
Cornea. 1990 Jan;9(1):81-5.
2
Paraproteinemic keratopathy associated with monoclonal gammopathy of undetermined significance (MGUS): clinical findings in twelve patients including recurrence after keratoplasty.与意义未明的单克隆丙种球蛋白血症(MGUS)相关的副蛋白血症性角膜病变:包括角膜移植术后复发在内的 12 例患者的临床发现。
Acta Ophthalmol. 2019 Nov;97(7):e987-e992. doi: 10.1111/aos.14123. Epub 2019 May 2.
3
kappa-Immunoglobulin corneal deposits associated with monoclonal gammopathy. Immunohistochemical and electron microscopic findings.与单克隆丙种球蛋白病相关的κ-免疫球蛋白角膜沉积物。免疫组织化学和电子显微镜检查结果。
Ger J Ophthalmol. 1994 Jan;3(1):54-7.
4
Paraproteinemic Keratopathy: The Expanding Diversity of Clinical and Pathologic Manifestations.副蛋白血症性角膜病变:临床表现和病理表现多样性的不断扩大。
Ophthalmology. 2015 Sep;122(9):1748-56. doi: 10.1016/j.ophtha.2015.05.029. Epub 2015 Jun 26.
5
Crystalline corneal deposits in monoclonal gammopathy: in-vivo confocal microscopy.单克隆丙种球蛋白病中的结晶性角膜沉积物:活体共聚焦显微镜检查
Semin Ophthalmol. 2013 Jan;28(1):37-40. doi: 10.3109/08820538.2012.730102.
6
Monoclonal corneal gammopathy: topographic considerations.单克隆角膜丙种球蛋白病:地形学考量
Ger J Ophthalmol. 1996 Sep;5(5):262-7.
7
Immunotactoid microtubular corneal deposits in bilateral paraprotein crystalline keratopathy and atypical corneal immunoglobulin deposition in a patient with dysproteinemia.双侧副蛋白结晶性角膜病变中的免疫触须样微管性角膜沉积物及一例蛋白异常血症患者的非典型角膜免疫球蛋白沉积
Cornea. 2011 Feb;30(2):247; author reply 247-8. doi: 10.1097/ICO.0b013e3181d52931.
8
Crystal-storing histiocytosis and crystalline keratopathy caused by monoclonal gammopathy of undetermined significance.意义未明的单克隆丙种球蛋白血症致晶体状贮积性组织细胞增多症和晶体状角膜病变。
Cornea. 2009 Oct;28(9):1081-4. doi: 10.1097/ICO.0b013e318199f73b.
9
Paraproteinemic keratopathy in monoclonal gammopathy of undetermined significance treated with primary keratoprosthesis: Case report, histopathologic findings, and world literature review.原发性角膜移植术治疗意义未明的单克隆丙种球蛋白病中的副蛋白血症性角膜病变:病例报告、组织病理学发现及世界文献综述
Medicine (Baltimore). 2017 Dec;96(50):e8649. doi: 10.1097/MD.0000000000008649.
10
Atypical corneal manifestations of multiple myeloma. A clinical, histopathologic, and immunohistochemical report.多发性骨髓瘤的非典型角膜表现。一份临床、组织病理学和免疫组织化学报告。
Cornea. 1989 Dec;8(4):274-80.

引用本文的文献

1
Monoclonal gammopathy presenting with paraproteinemic keratopathy documented with anterior segment OCT: a case report.前部节段光学相干断层扫描记录的伴副蛋白血症性角膜病变的单克隆丙种球蛋白病:一例报告
BMC Ophthalmol. 2025 Jul 1;25(1):356. doi: 10.1186/s12886-025-04161-1.
2
Prevalence of corneal findings and their interrelation with hematological findings in monoclonal gammopathy.单克隆丙种球蛋白病的角膜病变及其与血液学检查结果的相关性。
PLoS One. 2022 Oct 31;17(10):e0276048. doi: 10.1371/journal.pone.0276048. eCollection 2022.
3
Corneal Densitometry and In Vivo Confocal Microscopy in Patients with Monoclonal Gammopathy-Analysis of 130 Eyes of 65 Subjects.
单克隆丙种球蛋白病患者的角膜密度测量与活体共聚焦显微镜检查——65例受试者130只眼的分析
J Clin Med. 2022 Mar 26;11(7):1848. doi: 10.3390/jcm11071848.
4
The Hematologic Definition of Monoclonal Gammopathy of Undetermined Significance in Relation to Paraproteinemic Keratopathy (An American Ophthalmological Society Thesis).意义未明的单克隆丙种球蛋白病与副蛋白血症性角膜病变相关的血液学定义(美国眼科学会论文)
Trans Am Ophthalmol Soc. 2016 Aug;114:T7.
5
A case of crystalline keratopathy in monoclonal gammopathy of undetermined significance (MGUS).意义未明的单克隆丙种球蛋白病(MGUS)合并晶体性角膜病变1例。
Korean J Ophthalmol. 2011 Jun;25(3):202-5. doi: 10.3341/kjo.2011.25.3.202. Epub 2011 May 24.
6
Classic lattice corneal dystrophy associated with monoclonal gammopathy after exclusion of a TGFBI mutation.排除TGFBI突变后与单克隆丙种球蛋白病相关的经典格子状角膜营养不良。
Cornea. 2009 Jan;28(1):97-8. doi: 10.1097/ICO.0b013e31818200f4.