Infectious Disease Division, Winthrop-University Hospital, Mineola, New York 11501, USA.
Heart Lung. 2013 Mar-Apr;42(2):152-3. doi: 10.1016/j.hrtlng.2012.07.002. Epub 2012 Sep 11.
Fevers of unknown origin (FUOs) are classified according to the underlying disorder. The 4 main clinical categories of FUOs are infectious, malignant, rheumatic/inflammatory, and miscellaneous disorders. Although malignancy remains the most common cause of FUOs, rheumatic/inflammatory disorders remain important diagnostically and therapeutically. Rheumatic/inflammatory disorders, for example, systemic lupus erythematosus (SLE) presenting as FUO, have become uncommon in recent years because of better serologic diagnostic tests. However, SLE remains a rare but important cause of FUO in adults. SLE may be a difficult FUO diagnosis when a patient presents with fever without joint manifestations as the only symptoms of SLE. During the workup of the patient described in this article, the other causes of pericarditis were ruled out and SLE pericarditis was diagnosed. This is a rare case of an adult FUO with pericarditis as the only manifestation of SLE.
不明原因发热（FUO）根据潜在疾病进行分类。FUO 的 4 个主要临床类别为感染性、恶性、风湿/炎症性和其他疾病。尽管恶性肿瘤仍然是 FUO 的最常见原因，但风湿/炎症性疾病在诊断和治疗上仍然很重要。例如，由于更好的血清学诊断检测，近年来以 FUO 为表现的系统性红斑狼疮（SLE）等风湿/炎症性疾病已不常见。然而，SLE 仍然是成人 FUO 的一个罕见但重要的病因。当患者仅以发热且无关节表现为 SLE 的唯一症状就诊时，SLE 可能是一个难以诊断的 FUO。在本文所描述患者的检查过程中，排除了其他心包炎病因，并诊断为 SLE 心包炎。这是一个罕见的成人 FUO 病例，心包炎是 SLE 的唯一表现。
