Department of Dermatology, University of Connecticut Health Center, Farmington, Connecticut, USA.
J Am Acad Dermatol. 2012 Oct;67(4):515.e1-13; quiz 528-30. doi: 10.1016/j.jaad.2012.06.022.
Treatment of congenital melanocytic nevi (CMN) is generally undertaken for 2 reasons: (1) to reduce the chances of cutaneous malignant melanoma and (2) for cosmetic reasons. Over the past century, a large number of treatments for CMN have been described in the literature. These include excision, dermabrasion, curettage, chemical peels, radiation therapy, cryotherapy, electrosurgery, and lasers. Only low-level evidence supporting these approaches is available, and large randomized controlled trials have not been published. This article explores therapeutic controversies and makes recommendations based on the best available evidence.
先天性黑素细胞痣(CMN)的治疗通常出于以下两个原因:(1)降低皮肤恶性黑色素瘤的发生几率;(2)出于美容原因。在过去的一个世纪里,文献中已经描述了大量治疗 CMN 的方法。这些方法包括切除、磨皮、刮除、化学脱皮、放射治疗、冷冻疗法、电外科和激光。只有支持这些方法的低水平证据,并且尚未发表大型随机对照试验。本文探讨了治疗争议,并根据现有最佳证据提出建议。