De Jesus A, Talal N
Clinical Immunology Section, Audie L. Murphy Memorial Veterans Hospital, San Antonio, TX.
Crit Care Med. 1990 Feb;18(2 Suppl):S132-7.
Immunosuppressive drugs are frequently used in the treatment of autoimmune rheumatic diseases when more conventional therapy, including corticosteroids, fail to control the manifestations of disease. The practical use of these drugs in rheumatoid arthritis, systemic lupus erythematosus, and vasculitis (including Wegener's granulomatosis and Sjögren's syndrome) are reviewed. The focus is on the indications for the administration of these agents and proper monitoring of their effect on disease activity.
当包括皮质类固醇在内的更传统疗法无法控制自身免疫性风湿性疾病的表现时，免疫抑制药物经常被用于这些疾病的治疗。本文综述了这些药物在类风湿关节炎、系统性红斑狼疮和血管炎（包括韦格纳肉芽肿和干燥综合征）中的实际应用。重点是这些药物的给药指征以及对其对疾病活动影响的适当监测。
