苏丹喀土穆州公立教学医院医护人员的社会人口学特征与乙型肝炎病毒（HBV）感染情况
Socio-demographic characteristics of health care workers and hepatitis B virus (HBV) infection in public teaching hospitals in Khartoum State, Sudan.
作者信息
Ahmed Elmukashfi Taha, Ali Ibrahim Omer, Elkhidir Isam Mohamed, Ali Bashir Abdelgadir, Ali Awad Elkarim Mohammed
机构信息
Department of Community Medicine, Faculty of Medicine, University of Khartoum, Khartoum State, Sudan.
出版信息
Glob J Health Sci. 2012 May 21;4(4):37-41. doi: 10.5539/gjhs.v4n4p37.
BACKGROUND
HBV is second to tobacco as a known human carcinogen and the 10th leading cause of death worldwide.
OBJECTIVES
To examine the socio-demographic characteristics of health care workers and hepatitis B virus in Public Teaching Hospitals in Khartoum State, Sudan, in 2004.
METHODS
It was an observational, cross sectional, facility-based study. A total of 843 subjects were selected. It was conducted through multistage cluster sampling. The clustering was based on: type of hospital (Federal or State) and degree of exposure (type of department). For the analysis, Z-test for single proportion and some non-parametric tests such as Chi-Square test were used.
RESULTS
Among the 843 subjects tested for HBV markers (Anti-HBc, HBsAg, HBsAb, and HBeAg), the prevalence of Anti-HBc, HBsAg, HBsAb, and HBeAg was found to be 57%, 6%, 37% and 9% respectively. Seroprevalence of all HBV markers was found to be statistically significant with demographic factors (P<0.05).
CONCLUSION
Infection rate, carrier rate and a profile of high infectivity rate were found to be high. The immunity rate was low. There is a significant association between HBV markers and socio-demographic characteristics. Highest rate of infection was found in State Hospitals, South and West regions, married HCWs and HCWs of age group 30-49.
背景
乙肝病毒是仅次于烟草的已知人类致癌物，是全球第十大死因。
目的
研究2004年苏丹喀土穆州公立教学医院医护人员及乙肝病毒的社会人口学特征。
方法
这是一项基于机构的观察性横断面研究。共选取843名受试者。通过多阶段整群抽样进行。整群抽样基于：医院类型（联邦或州）和暴露程度（科室类型）。分析时，使用了单比例Z检验和一些非参数检验，如卡方检验。
结果
在843名检测乙肝病毒标志物（抗-HBc、HBsAg、HBsAb和HBeAg）的受试者中，抗-HBc、HBsAg、HBsAb和HBeAg的流行率分别为57%、6%、37%和9%。发现所有乙肝病毒标志物的血清流行率与人口统计学因素在统计学上有显著差异（P<0.05）。
结论
发现感染率、携带率和高感染率情况较高。免疫率较低。乙肝病毒标志物与社会人口学特征之间存在显著关联。在州立医院、南部和西部地区、已婚医护人员以及30-49岁年龄组的医护人员中发现感染率最高。
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