Gastroenterology Department, Faculty of Medicine, Kinshasa University, Congo DR.
Department of Public Health, School of Medicine, International University of Health and Welfare, Japan.
Ind Health. 2019 Sep 26;57(5):621-626. doi: 10.2486/indhealth.2018-0166. Epub 2019 Jan 23.
We aimed to determine hepatitis B virus (HBV) prevalence and risk factors for health care workers (HCWs) to contract HBV infection in a referral hospital in the Democratic Republic of Congo. From October 2015 to August 2016, we recruited 97 HCWs (55 males and 42 females, aged 41.2 ± 10 yr) from Kisantu St. Luke's Hospital, a Congolese referral hospital located in the province of Kongo Central. Serum samples were assayed for HBV markers using ELISA. A questionnaire was used to record the HCWs' demographics, medical histories, and risk factors. The overall prevalence of exposure to HBV infection [HBsAg+, and/or hepatitis B core antibody (anti-HBc)+] was 56.7% (55/97). HBsAg positivity was found in 18.6% (18/97) of the HCWs whereas 29.9% (29/97) were anti-HBc positive. Approximately 8.2% (8/97) of the HCWs tested positive for both HBsAg and anti-HBc. Being a physician [odds ratio (OR)=2.8 (95% CI: 1.34-12.23)], a laboratory technician [OR=3.35 (95% CI: 1.35-5.21)], and having multiple sex partners [OR=3.05 (95% CI: 1.13-9.09)] were found to be factors associated with HBV infection. Exposure to HBV is common among HCWs at Kisantu St. Luke's Hospital. Isolated HBsAg was also prevalent among them. There is a high risk that HBV could be spread to others. Therefore, there is an urgent need for HBV screening, treatment, and vaccination policies.
我们旨在确定在刚果民主共和国的一家转诊医院中乙型肝炎病毒 (HBV) 的流行情况以及卫生保健工作者 (HCWs) 感染 HBV 的危险因素。2015 年 10 月至 2016 年 8 月，我们从位于刚果中央省的刚果转诊医院 Kisantu St. Luke's Hospital 招募了 97 名 HCWs（55 名男性和 42 名女性，年龄 41.2±10 岁）。使用酶联免疫吸附试验 (ELISA) 检测血清样本中的 HBV 标志物。使用问卷记录 HCWs 的人口统计学、病史和危险因素。HBV 感染暴露的总体患病率[HBsAg+，和/或乙型肝炎核心抗体 (抗-HBc)+]为 56.7%（55/97）。18.6%（18/97）的 HCWs 出现 HBsAg 阳性，29.9%（29/97）抗-HBc 阳性。大约 8.2%（8/97）的 HCWs 同时检测到 HBsAg 和抗-HBc 阳性。作为医生[比值比 (OR)=2.8（95%置信区间：1.34-12.23)]，实验室技术员[OR=3.35（95%置信区间：1.35-5.21)]和有多个性伴侣[OR=3.05（95%置信区间：1.13-9.09)]被发现与 HBV 感染相关。Kisantu St. Luke's Hospital 的 HCWs 中普遍存在 HBV 暴露。他们中也有很高的 HBsAg 单独感染率。HBV 传播给他人的风险很高。因此，迫切需要制定 HBV 筛查、治疗和疫苗接种政策。
