Tu Shu-Fen, Chou Yu-Ching, Sun Chien-An, Hsueh Shu-Chun, Yang Tsan
Chen Xiangguo Joint Clinics, Tainan, Taiwan.
Glob J Health Sci. 2012 Jul 18;4(5):53-62. doi: 10.5539/gjhs.v4n5p53.
The purpose of this study was to evaluate the prevalence of metabolic syndrome (MetS) among hemodialysis patients and factors associated with quality of dialysis.
Data were collected from 377 long-term hemodialysis patients who received hemodialysis treatment from clinics in Tainan and Kaohsiung between November 2009 and February 2010. MetS was defined using the criteria set in 2007 by the Bureau of Health Promotion, Department of Health, Taiwan. The measurement of Kt/V was used as an indicator of the quality of dialysis. A below 1.4 Kt/V was considered poor dialysis quality.
Results showed that the prevalence of MetS among the chronic hemodialysis patients in this sample was 63.1%. Logistic regression results identified that the quality of dialysis in females was better than that in males (odds ratio (OR)=7.98, 95% confidence interval (CI): 2.52-25.31). Better quality dialysis was associated with older age, longer treatment time, and increased blood flow rate (OR=1.49, 13.63, and 1.35, respectively). However, for every one kilogram increase in weight, the quality of dialysis decreased by 13 percents (OR=0.87, 95% CI: 0.83-0.92).
MetS is common among hemodialysis patients. The prevalence of hypertension, hyperlipidemia, and hyperglycaemia were significantly higher among hemodialysis patients. Quality of dialysis related to gender, age, weight, and the dialysis prescription (treatment time and blood flow rate).
本研究旨在评估血液透析患者中代谢综合征(MetS)的患病率以及与透析质量相关的因素。
收集了2009年11月至2010年2月间在台南和高雄诊所接受血液透析治疗的377例长期血液透析患者的数据。采用台湾卫生署健康促进局2007年设定的标准来定义MetS。Kt/V的测量被用作透析质量的指标。Kt/V低于1.4被认为透析质量较差。
结果显示,该样本中慢性血液透析患者MetS的患病率为63.1%。逻辑回归结果表明,女性的透析质量优于男性(优势比(OR)=7.98,95%置信区间(CI):2.52 - 25.31)。透析质量较好与年龄较大、治疗时间较长和血流速度增加有关(OR分别为1.49、13.63和1.35)。然而,体重每增加1千克,透析质量下降13%(OR = 0.87,95% CI:0.83 - 0.92)。
MetS在血液透析患者中很常见。血液透析患者中高血压、高脂血症和高血糖症的患病率明显更高。透析质量与性别、年龄、体重以及透析处方(治疗时间和血流速度)有关。