脑脊液犬尿酸与精神分裂症谱系精神病的自杀风险。
CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis.
机构信息
Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden.
出版信息
Psychiatry Res. 2013 Jan 30;205(1-2):165-7. doi: 10.1016/j.psychres.2012.08.021. Epub 2012 Sep 11.
Abstract
Relationships between concentrations of cerebrospinal fluid (CSF) kynurenic acid (KYNA) and suicidal behavior were evaluated in 59 patients with psychosis after 22 years of follow-up. Three patients died from suicide and nine patients had a history of attempted suicide. Patients with attempted suicide had significantly lower concentrations of CSF KYNA.
摘要
在对 59 名精神病患者进行了 22 年的随访后，评估了脑脊液（CSF）犬尿氨酸（KYNA）浓度与自杀行为之间的关系。有 3 名患者死于自杀，9 名患者有自杀未遂史。有自杀未遂史的患者脑脊液 KYNA 浓度明显降低。
Zotero 插件