The University of Adelaide, South Australia, Australia.
Int J Technol Assess Health Care. 2012 Jul;28(3):211-9. doi: 10.1017/S0266462312000402.
The aim of this study was to determine how evidence from systematic review (SR) is perceived and negotiated by expert stakeholders in considering a technology for potential disinvestment.
An evidence-informed stakeholder engagement examined results from a diagnostic accuracy SR of vitamin B12 and folate tests. Pathologists deliberated around the SR findings to generate an informed contribution to future policy for the funding of B12 and folate tests. Deliberations were transcribed and subject to qualitative analysis.
Pathologists did not engage with findings from the SR in depth; rather they sought to contest the terms of the problem driving the review and attempted to reframe it. Pathologists questioned the usefulness of SR outcomes given the variable definitions of B12 deficiency and deferred addressing disinvestment options specifically pertaining to B12 testing. However, folate testing was proffered as a potential disinvestment candidate, based upon pathologists' definition of "appropriate" evidence beyond the bounds of the SR.
The value of SR to informing disinvestment deliberations by expert stakeholders may be a function of timing as well as content. Engagement of stakeholders in co-produced evidence may be required at two levels: (i) Early in the synthesis phase to help shape the SR and harmonize expert views with the available evidence (including gaps); (ii) Collaboration in primary research to fill evidence-gaps thus supporting evidence-based disinvestment. Without this, information asymmetry between clinically engaged experts and decision makers may preclude the collaborative, informed, and technical discussions required to generate productive policy change.
本研究旨在确定系统评价(SR)的证据如何被考虑潜在撤资技术的专家利益相关者感知和协商。
一项基于证据的利益相关者参与研究,对维生素 B12 和叶酸检测的诊断准确性 SR 的结果进行了检查。病理学家围绕 SR 研究结果进行了审议,以便为 B12 和叶酸检测的未来政策提供信息。审议内容被转录并进行了定性分析。
病理学家没有深入研究 SR 的结果;相反,他们试图对推动审查的问题的条件提出质疑,并试图重新定义它。病理学家质疑 SR 结果的有用性,因为 B12 缺乏的定义不同,并推迟专门针对 B12 检测的撤资方案。然而,根据病理学家对超出 SR 范围的“适当”证据的定义,叶酸检测被提议为一种潜在的撤资候选者。
SR 对专家利益相关者参与撤资审议的价值可能是由时间和内容决定的。在两个层面上需要利益相关者参与共同制定证据:(i)在综合阶段早期,以帮助塑造 SR 并协调专家意见与现有证据(包括差距);(ii)在初级研究中进行合作,以填补证据差距,从而支持基于证据的撤资。如果没有这些,临床参与专家和决策者之间的信息不对称可能会阻碍产生富有成效的政策变革所需的协作、知情和技术讨论。