Hocar O, Madhar M, Akhdari N, Rais H, Belaabidia B, Fikry T, Amal S
Service de dermatologie, université Cadi Ayyad, CHU Mohammed VI, Marrakech, Maroc.
Chir Main. 2012 Sep;31(4):217-9. doi: 10.1016/j.main.2012.07.007. Epub 2012 Aug 9.
Myxoid neurofibroma (MN) is a benign tumor of poorly identified perineural cell origin. We report a case of NM of left thumb and discuss the main differential diagnosis.
A 34-year-old woman presented with a painless, slowly progressive tumor of the left thumb of 6 months duration. This tumor had recurred after resection done 26 years before. Clinical examination revealed a tumor on the anterior surface of the left thumb, painless, firm, 4×3cm, ulcerated and covered with thin telangiectasia. The X-ray of the phalanx showed no alteration to the underlying bone. The histopathological study of a skin biopsy reported a myxoid neurofibroma. Excision of the lesion was performed with preservation of the nail. Neither the patient nor her family members had neurofibromatosis. The outcome was favorable and no recurrence was noted after 18 months of follow-up.
The usual sites of the MN are the face, shoulders, arms, and periungual regions. It is usually a solitary lesion; however, lesions may be multiple or recur after initial incomplete excision as in our patient. It must be considered in the differential diagnosis of tumors of the extremities. We report this case because of the rarity of both the tumor and its site.
黏液样神经纤维瘤（MN）是一种起源于神经周细胞、来源不明的良性肿瘤。我们报告一例左拇指黏液样神经纤维瘤病例，并讨论主要的鉴别诊断。
一名34岁女性，左拇指出现一个无痛性、缓慢生长6个月的肿瘤。该肿瘤在26年前切除后复发。临床检查发现左拇指前表面有一个肿瘤，无痛，质地硬，4×3厘米，有溃疡，表面覆盖着细小的毛细血管扩张。指骨X线检查显示其下方骨骼无改变。皮肤活检的组织病理学研究报告为黏液样神经纤维瘤。在保留指甲的情况下对病变进行了切除。患者及其家属均无神经纤维瘤病。结果良好，随访18个月未发现复发。
黏液样神经纤维瘤的常见部位是面部、肩部、手臂和甲周区域。它通常是单发病变；然而，病变可能多发，或如我们的患者一样，在初次切除不完全后复发。在四肢肿瘤的鉴别诊断中必须考虑到它。我们报告这个病例是因为该肿瘤及其部位都很罕见。
