在中国人群中，神经调节蛋白 3 没有遗传证据表明其与精神分裂症风险相关。
No genetic evidence for Neuregulin 3 conferring risk of schizophrenia in the Chinese population.
机构信息
Department of Genetics and Molecular Biology, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710061, PR China.
出版信息
Psychiatry Res. 2013 Feb 28;205(3):279-81. doi: 10.1016/j.psychres.2012.08.017. Epub 2012 Sep 13.
Abstract
We genotyped 13 single nucleotide polymorphisms (SNPs) within Neuregulin 3 (NRG3) to investigate the association between NRG3 and schizophrenia in 488 patients and 506 controls in Northwest China. No association was detected either in SNPs or in haplotypes. Our study provided no evidence that NRG3 confers a risk of schizophrenia susceptibility in the Han Chinese population.
摘要
我们对神经调节蛋白 3（NRG3）中的 13 个单核苷酸多态性（SNPs）进行了基因分型，以研究 NRG3 与中国西北地区 488 例患者和 506 例对照者精神分裂症之间的关系。无论是在 SNP 还是在单体型中，均未检测到相关性。我们的研究没有提供证据表明 NRG3 会使汉族人群易患精神分裂症。
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