Department of Neurology, Faculty of Medicine, Assiut University, Egypt.
Epilepsy Res. 2013 Mar;104(1-2):167-74. doi: 10.1016/j.eplepsyres.2012.08.010. Epub 2012 Sep 13.
Epilepsy is one of the serious neurological disorders which results in profound morbidity and mortality. Although epilepsy has no geographical boundaries, understanding cultural, social, and economic backgrounds is a very important step for interpretation of its epidemiological characteristics. This work aims to study the epidemiological profile of epilepsy in New Valley Governorate and to estimate its magnitude of treatment gap. It was conducted in a door to door survey, including all inhabitants (62,583 subjects), by 3 neurologists to detect any suspected case of focal or generalized epilepsy. All suspected cases were subjected to detailed history, clinical examination, EEG, neuroimaging studies, and estimation of serum drug level if needed. The study revealed that life time prevalence of epilepsy in Al Kharga district is 6.76/1000, with highest peak during early child hood, while that of active epilepsy is 4.99/1000 population. The annual incidence rate is 43.14/100,000, and age specific incidence rate has a U-shaped pattern with two peaks of incidence at early infancy and elderly. Localization-related epilepsy is the most frequently encountered type (53.7%). However the treatment gap of epilepsy in New Valley is similar to that in developing countries (61.5%).
Prevalence and Incidence Rate of epilepsy in New Valley are similar to that in industrialized countries.
癫痫是一种严重的神经系统疾病，会导致严重的发病率和死亡率。尽管癫痫没有地域界限，但了解文化、社会和经济背景对于解释其流行病学特征非常重要。本研究旨在研究新河谷省癫痫的流行病学特征，并估计其治疗差距的程度。该研究采用了门到门的调查方法，由 3 名神经病学家对 62,583 名居民进行了调查，以发现任何局灶性或全身性癫痫的疑似病例。所有疑似病例均接受详细的病史、临床检查、脑电图、神经影像学研究以及必要时的血清药物水平评估。研究表明，在 Al Kharga 地区，癫痫的终生患病率为 6.76/1000，儿童早期患病率最高，而活动性癫痫的患病率为 4.99/1000 人口。年发病率为 43.14/100,000，年龄特异性发病率呈 U 形模式，在婴儿期和老年期有两个发病高峰。与定位相关的癫痫是最常见的类型（53.7%）。然而，新河谷省的癫痫治疗差距与发展中国家相似（61.5%）。
新河谷省的癫痫患病率和发病率与工业化国家相似。
