Naumenko O I
Eksp Onkol. 1990;12(1):25-31.
The population of leukemic cells (beginning from the precursor cells) has been identified by electron-microscopy methods. Ultrastructural changes typical of the erythropoiesis alteration are determined. Peculiarities in the formation of a leukemic cells population in different hemopoietic organs and changes in erythroid islands (the main morphofunctional unit of erythropoiesis) are revealed. Data obtained show the significant disturbances in differentiation of erythroid cells in the virus leukoses and are very important form the further study of the leukemogenesis mechanisms.
通过电子显微镜方法已鉴定出白血病细胞群体(从前体细胞开始)。确定了红细胞生成改变所特有的超微结构变化。揭示了不同造血器官中白血病细胞群体形成的特点以及红系岛(红细胞生成的主要形态功能单位)的变化。所获得的数据表明病毒白血病中红细胞系细胞分化存在明显紊乱,这对于进一步研究白血病发生机制非常重要。