Department of Engineering Mechanics, Institute of High Performance Computing, A(*)Star, Singapore 138632, Singapore.
Comput Biol Med. 2012 Nov;42(11):1060-3. doi: 10.1016/j.compbiomed.2012.08.007. Epub 2012 Sep 14.
Vascular support structures are important devices for treating valve stenosis. Large population of patients is treated for valvular disease and the principal mode of treatment is the use of percutaneous valvuloplasty. Stent devices are proving to be an improved technology in minimal invasive cardiac surgery. This technology now accounts for 20% of treatments in Europe. This new technology provides highly effective results at minimal cost and short duration of hospitalization. During the development process, a number of specific designs and materials have come and gone, and a few have remained. Many design changes were successful, and many were not. This paper discusses the physical behavior of a hooked percutaneous aortic valve stent design using a finite element analysis. Specifically, the effects of crimping was simulated and analyzed for two types of realistic but different Nitinol materials (NITI-1 and NITI-2). The results show that both NITI-1 and NITI-2 had good crimping performance. The analysis performed in this paper may aid in understanding the stent's displacement ranges when subjected to physiological pressures exerted by the heart and cardiac blood flow during abnormal cardiovascular conditions. It may also help to evaluate the suitability of a Nitinol for fabrication purposes.
血管支撑结构是治疗瓣膜狭窄的重要装置。大量瓣膜疾病患者接受治疗，主要治疗方式是经皮瓣膜成形术。支架设备在微创心脏手术中被证明是一种改进的技术。这项技术现在占欧洲治疗方法的 20%。这种新技术以最低的成本和最短的住院时间提供了非常有效的结果。在开发过程中，出现了许多特定的设计和材料，其中一些保留了下来。许多设计变更取得了成功，也有许多没有成功。本文使用有限元分析讨论了一种钩状经皮主动脉瓣支架设计的物理行为。具体来说，模拟并分析了两种实际但不同的 Nitinol 材料（NITI-1 和 NITI-2）的卷曲效果。结果表明，NITI-1 和 NITI-2 都具有良好的卷曲性能。本文进行的分析可以帮助理解支架在异常心血管条件下，心脏和心内血流施加的生理压力下的位移范围。它还可以帮助评估 Nitinol 用于制造目的的适用性。
