Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria 3800, Australia.
Dev Biol. 2012 Dec 1;372(1):1-4. doi: 10.1016/j.ydbio.2012.08.031. Epub 2012 Sep 8.
Zebrafish is a common model organism in research and yet, despite its widespread use, anatomical resources for this species are incomplete or lacking in functionality. There remains a need for a single reference resource that integrates user-friendly tools to facilitate the identification of structures, display of reference images, provides data on gene expression, links to relevant literature, and covers the complete range of zebrafish developmental stages. To fulfill this need, we have designed the Zebrafish Anatomy Portal (www.zfap.org), containing annotated three-dimensional images of zebrafish at stages throughout development and adulthood, acquired by optical projection tomography. ZFAP combines functionalities to allow scanning through 3D data sets, searching of images by anatomical terms, predictions of gene expression from literature analysis, and facilitation of the identification of relevant literature through assisted searching of the NCBI PubMed resource. ZFAP provides a highly functional anatomical resource that will aid future education and research in the zebrafish model system.
斑马鱼是一种常见的研究模式生物，但尽管其应用广泛，该物种的解剖学资源仍不完整或缺乏功能。我们仍然需要一个集成了用户友好工具的单一参考资源，以方便识别结构、显示参考图像、提供基因表达数据、链接到相关文献，并涵盖斑马鱼发育阶段的完整范围。为了满足这一需求，我们设计了斑马鱼解剖学门户（www.zfap.org），其中包含通过光学投影断层扫描获得的发育和成年阶段斑马鱼的三维注释图像。ZFAP 结合了各种功能，允许通过 3D 数据集进行扫描、通过解剖学术语搜索图像、通过文献分析预测基因表达，以及通过辅助搜索 NCBI PubMed 资源来方便识别相关文献。ZFAP 提供了一个功能强大的解剖学资源，将有助于斑马鱼模型系统的未来教育和研究。
