School of Biological Sciences, Monash University, Melbourne, Victoria 3800, Australia, The Murdoch Childrens Research Institute, The Royal Children's Hospital, Flemington Road, Parkville, Melbourne, Victoria 3052, Australia, Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia, Aix Marseille Université, Inserm, GMGF UMR_S 910, 13385 Marseille, France, Instituto Gulbenkian de Ciencia, Rua da Avenida Grande 6, 2780-156 Oeiras, Portugal and Centre for Environmental Biology, Faculdade de Ciencias da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.
Database (Oxford). 2014 Apr 7;2014(0):bau028. doi: 10.1093/database/bau028. Print 2014.
The Japanese quail is a widely used model organism for the study of embryonic development; however, anatomical resources are lacking. The Quail Anatomy Portal (QAP) provides 22 detailed three-dimensional (3D) models of quail embryos during development from embryonic day (E)1 to E15 generated using optical projection tomography. The 3D models provided can be virtually sectioned to investigate anatomy. Furthermore, using the 3D nature of the models, we have generated a tool to assist in the staging of quail samples. Volume renderings of each stage are provided and can be rotated to allow visualization from multiple angles allowing easy comparison of features both between stages in the database and between images or samples in the laboratory. The use of JavaScript, PHP and HTML ensure the database is accessible to users across different operating systems, including mobile devices, facilitating its use in the laboratory.The QAP provides a unique resource for researchers using the quail model. The ability to virtually section anatomical models throughout development provides the opportunity for researchers to virtually dissect the quail and also provides a valuable tool for the education of students and researchers new to the field. DATABASE URL: http://quail.anatomyportal.org (For review username: demo, password: quail123).
日本鹌鹑是研究胚胎发育的广泛使用的模式生物;然而,解剖学资源却很缺乏。鹌鹑解剖资源库(QAP)提供了 22 个详细的三维(3D)模型,这些模型是使用光学投影断层扫描技术生成的,涵盖了从胚胎日(E)1 到 E15 的发育过程中的鹌鹑胚胎。提供的 3D 模型可以进行虚拟切片,以研究解剖结构。此外,我们还利用模型的 3D 性质,生成了一个工具,以协助对鹌鹑样本进行分期。每个阶段的体积渲染都提供了,并可以旋转,以便从多个角度进行可视化,从而便于在数据库中的各个阶段之间以及在实验室中的图像或样本之间进行特征比较。使用 JavaScript、PHP 和 HTML 确保数据库可以在不同的操作系统上访问,包括移动设备,方便其在实验室中的使用。QAP 为使用鹌鹑模型的研究人员提供了一个独特的资源。在整个发育过程中对解剖模型进行虚拟切片的能力为研究人员提供了虚拟解剖鹌鹑的机会,也为该领域的新手学生和研究人员提供了有价值的教育工具。数据库 URL:http://quail.anatomyportal.org(审查时的用户名:demo,密码:quail123)。