Hernández Fernández Carlos, Brenes Bermúdez Francisco, Moncada Iribarren Ignacio
Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Med Clin (Barc). 2012 Dec 1;139(13):582-7. doi: 10.1016/j.medcli.2012.06.006. Epub 2012 Sep 14.
To review the role of α-blockers in various urological conditions such as benign prostatic hyperplasia, overactive bladder, chronic prostatitis, and erectile dysfunction and as expulsive treatment of distal ureteral stones.
We reviewed the latest scientific evidence in all the fields mentioned above, performing a critical analysis.
α-blockers are now considered first-line treatment in lower urinary tract symptoms secondary to benign prostatic hyperplasia, but the indications go beyond, and are able to improve, alone or in combination with other drugs, the previously mentioned pathologies. The uroselective properties of some α-blockers make them a highly safe medication.
综述α受体阻滞剂在各种泌尿系统疾病中的作用，如良性前列腺增生、膀胱过度活动症、慢性前列腺炎和勃起功能障碍，以及作为远端输尿管结石的排石治疗。
我们回顾了上述所有领域的最新科学证据，并进行了批判性分析。
α受体阻滞剂目前被认为是良性前列腺增生继发下尿路症状的一线治疗药物，但其适应证不止于此，能够单独或与其他药物联合改善上述疾病。一些α受体阻滞剂的尿路选择性特性使其成为一种高度安全的药物。
