糖醛衍生物与醇在 N-溴代丁二酰亚胺和二苯基二硒醚存在下的反应：2-脱氧-2-苯硒基糖苷的制备。
Reaction of glycal derivatives with alcohols in the presence of N-bromosuccinimide and diphenyldiselenide: preparation of 2-deoxy-2-phenylselenyl glycosides.
机构信息
Bose Institute, Division of Molecular Medicine, P-1/12, CIT Scheme VII-M, Kolkata 700054, India.
出版信息
Carbohydr Res. 2012 Nov 1;361:41-8. doi: 10.1016/j.carres.2012.08.009. Epub 2012 Aug 21.
PMID:22982170
Abstract
Reaction of glycal derivatives with alcohols or glycosyl acceptors in the presence of N-bromosuccinimide (NBS) and diphenyldiselenide resulted in the formation of alkyl 2-deoxy-2-phenylselenyl glycosides or disaccharide derivatives in excellent yield. The reactions are reasonably fast and considerable stereo-selectivity was observed in the preparation of disaccharide derivatives.
摘要
在 N-溴代丁二酰亚胺（NBS）和二苯基二硒醚存在下，糖醛衍生物与醇或糖基受体反应，生成了烷基 2-脱氧-2-苯硒基糖苷或二糖衍生物，产率优异。这些反应速度相当快，在二糖衍生物的制备中观察到了相当大的立体选择性。
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