Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China.
Food Chem Toxicol. 2012 Dec;50(12):4285-91. doi: 10.1016/j.fct.2012.08.052. Epub 2012 Sep 13.
Xiamen is a representative coastal city in China. Shellfish is widely consumed by local people. A broad spectrum of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) were measured in representative shellfish from Xiamen. Despite being banned many years ago, these chemicals were still detected at varying levels. The total PCB levels ranged from 0.48 to 3.28 ng/g wet wt. for the shellfish surveyed. The tetra-, penta- and hexa-PCB congeners were found to be predominant. The estimated WHO-TEQ PCB intakes through shellfish consumption ranged from 0.063 to 0.102 pg/kg body wt. for Xiamen adults and children, which were significantly lower than tolerable weekly intake. Among OCPs, DDTs were predominant, followed by aldrin-like chemicals and endosulfans. The increase in aldrin-like chemicals and endosulfans, and the decrease in DDTs were observed in this study when compared to historical data in Xiamen. HCHs, chlordanes, HCB, heptachlors and mirex were detected with low concentrations in the shellfish. The estimated intakes of OCPs were several orders lower than tolerable daily intakes. However, the high carcinogenic risk of aldrin and dieldrin were found in the measured shellfish species. p,p'-DDD, p'p-DDT, α-HCH and β-HCH in certain species should also be concerned for their potential carcinogenic risks.
厦门是中国沿海的一个代表性城市。当地人广泛食用贝类。本研究检测了厦门代表性贝类中的多种多氯联苯（PCBs）和有机氯农药（OCPs）。尽管这些化学物质多年前已被禁用，但仍在不同程度上被检测到。调查贝类中的总 PCB 水平范围为 0.48 至 3.28ng/g 湿重。四氯、五氯和六氯 PCB 同系物是主要的存在形式。通过食用贝类摄入的估计 WHO-TEQ PCB 范围为 0.063 至 0.102pg/kg 体重，厦门成年人和儿童的摄入量明显低于可耐受每周摄入量。在 OCPs 中，滴滴涕（DDTs）是主要的，其次是艾氏剂类化学物质和硫丹。与厦门的历史数据相比，本研究中观察到艾氏剂类化学物质和硫丹的增加以及滴滴涕的减少。贝类中检测到低浓度的六氯环己烷（HCHs）、氯丹、六氯苯（HCB）、七氯和灭蚁灵。OCPs 的估计摄入量比可耐受每日摄入量低几个数量级。然而，在所测贝类物种中发现了艾氏剂和狄氏剂的高致癌风险。某些物种中的 p,p'-DDD、p'p-DDT、α-HCH 和 β-HCH 也应关注其潜在的致癌风险。
