Urry R L, Heaton J B, Moore M, Middleton R G
Division of Urology, University of Utah School of Medicine, Salt Lake City 84132.
Fertil Steril. 1990 Feb;53(2):341-5. doi: 10.1016/s0015-0282(16)53292-0.
Semen quality was evaluated in 256 men at 2, 4, 6, and 12 months after vasectomy reversal. Total sperm counts were normal and averaged 91 X 10(6) sperm per ejaculate. The percentage of live sperm was decreased below normal to 36% and hypo-osmolarity values indicated only 41% of the sperm with normal membranes. Progressive motility and the total progressively motile sperm count were reduced and averaged 25% and 27 million, respectively. Approximately 50% of the patients had positive titers of sperm agglutinating and/or sperm immobilizing antibodies. Sperm morphology indicated tail and head shape defects with increases in both tapered and immature sperm. A fertility score combining several sperm parameters averaged only 37% of normal. All of these values remained constant with time after reversal except for progressive motility (increased), oval head shapes (increased), and tapered sperm (decreased). This study has demonstrated that characteristic defects occur in sperm (decreased). This study has demonstrated that characteristic defects occur in sperm motility, sperm membrane function and morphology, in addition to specimen fertility scores, after a vasectomy reversal and need to be taken into consideration when advising and treating these patients for subsequent fertility difficulties.
在输精管复通术后2个月、4个月、6个月和12个月对256名男性的精液质量进行了评估。精子总数正常，每次射精平均为9.1×10⁶个精子。活精子百分比降至正常水平以下，为36%，低渗值表明只有41%的精子膜正常。进行性运动能力和进行性运动精子总数减少，平均分别为25%和2700万。约50%的患者精子凝集和/或精子制动抗体滴度呈阳性。精子形态显示尾部和头部形状缺陷，锥形和未成熟精子均增加。综合多个精子参数的生育力评分平均仅为正常水平的37%。除了进行性运动能力（增加）、椭圆形头部形状（增加）和锥形精子（减少）外，所有这些值在复通后的时间里保持不变。这项研究表明精子存在特征性缺陷（减少）。这项研究表明，输精管复通术后，除了样本生育力评分外，精子运动能力、精子膜功能和形态也会出现特征性缺陷，在为这些患者提供咨询和治疗后续生育困难时需要考虑这些因素。
