用于预测周期刺激期间短暂性高催乳素血症的胃复安激发试验。

The metoclopramid-provocation test for prediction of transient hyperprolactinemia during cycle stimulation.

作者信息

Reinthaller A, Neunteufel W, Bieglmayer C, Fischl F

机构信息

Second Department of Obstetrics and Gynecology, University of Vienna Medical School, Austria.

出版信息

Fertil Steril. 1990 Feb;53(2):368-71. doi: 10.1016/s0015-0282(16)53300-7.

DOI:10.1016/s0015-0282(16)53300-7

PMID:2298320

Abstract

The predictive value of the metoclopramid-provocation test to detect transient hyperprolactinemia during cycle stimulation was assessed. Patients developing hyperprolactinemia during cycle stimulation showed a significantly higher PRL response to the metoclopramid-provocation test before cycle stimulation. The current study confirms previous reports that hyperprolactinemia during cycle stimulation can interfere with follicular and oocyte maturation. The use of the metoclopramid-test can detect an enhanced responsiveness to PRL stimulators and offers the possibility of treatment during cycle stimulation.

摘要

评估了甲氧氯普胺激发试验在周期刺激期间检测短暂高催乳素血症的预测价值。在周期刺激期间出现高催乳素血症的患者在周期刺激前对甲氧氯普胺激发试验的催乳素反应明显更高。本研究证实了先前的报道，即周期刺激期间的高催乳素血症会干扰卵泡和卵母细胞成熟。甲氧氯普胺试验的应用可以检测出对催乳素刺激剂的反应增强，并为周期刺激期间的治疗提供了可能性。