Voronkova K V, Kholin A A, Koroleva N Iu, Buchneva I A, Akhmedov T M, Mazal'skaia O V, Ermolenko N A
Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(6 Pt 2):4-11.
Idiopathic generalized epilepsies (IGE), in some cases, have focal features in the kinematic of seizures and in the EEG. The aim of the paper was to study these clinical phenomena using video-EEG monitoring. We studied 180 patients (80 men and 100 women) with different forms of IGE with epileptic seizures recorded with this method. The effect of the "superposition" of focal electro-clinical features on the kinematic matrix and EEG pattern of the generalized myo- (clonic)-tonic-clonic seizures was noted. The authors suggest to discuss the definition of the "phenomenon of secondary focalization". This is the clinical/electroencephalographic phenomenon developed in IGE and presented by the appearance of secondary focal features (clinical and electroencephalographic) in the structure of the generalized epileptic seizure. The evidence for the secondary generalization of the seizure with the presence of the regional cortical ictogenic source as well as the diagnosis of focal epilepsy are the exclusion criteria for the phenomenon of secondary focalization.
特发性全身性癫痫（IGE）在某些情况下，其癫痫发作的运动学及脑电图表现具有局灶性特征。本文旨在通过视频脑电图监测研究这些临床现象。我们研究了180例（80名男性和100名女性）患有不同类型IGE且采用该方法记录到癫痫发作的患者。注意到局灶性电临床特征的“叠加”对全身性肌阵挛（阵挛性）-强直-阵挛性发作的运动学矩阵和脑电图模式的影响。作者建议讨论“继发性局灶化现象”的定义。这是一种在IGE中出现的临床/脑电图现象，表现为在全身性癫痫发作结构中出现继发性局灶性特征（临床和脑电图方面）。癫痫发作存在区域皮质致痫源的继发性泛化证据以及局灶性癫痫的诊断是继发性局灶化现象的排除标准。
