Bisogno Gianni, Tagarelli Arianna, Stramare Roberto, Beltrame Valeria, Carli Modesto
Department of Pediatrics, Division of Hematology/Oncology, University Hospital of Padova, Padova, Italy.
J Pediatr Hematol Oncol. 2013 May;35(4):e171-3. doi: 10.1097/MPH.0b013e3182678d25.
Aggressive fibromatosis is a rare tumor of borderline malignancy with a marked local aggressiveness. Surgery is the mainstay of treatment but complete tumor resection is often not easy to achieve without functional and cosmetic sequelae. We report a case of a pretreated child with aggressive fibromatosis who responded to hydroxyurea, avoiding the need for demolitive surgery.
侵袭性纤维瘤病是一种罕见的交界性恶性肿瘤，具有明显的局部侵袭性。手术是主要的治疗方法，但在不产生功能和美容后遗症的情况下，实现肿瘤完全切除往往并不容易。我们报告一例经预处理的侵袭性纤维瘤病患儿，其对羟基脲有反应，从而避免了进行破坏性手术。
