Stengel Gabriele, Metze Dieter, Dörflinger Bernd, Luger Thomas A, Böhm Markus
Department of Dermatology, University of Münster, Münster, Germany.
J Am Acad Dermatol. 2008 Aug;59(2 Suppl 1):S7-9. doi: 10.1016/j.jaad.2007.07.019.
Aggressive fibromatosis (desmoid tumor) is a very rare neoplasm arising from the musculoaponeurotic structures. It is characterized by locally aggressive growth, and a tendency to relapse but not to metastasize. We report on a young woman with a large desmoid tumor of the left foot. Multiple operations and radiotherapy had resulted in local recurrences. Long-term immunointervention with pegylated interferon alfa-2b, however, led to marked clinical improvement of the patient's condition and a radiologically proven stabilization of the disease.
侵袭性纤维瘤病（韧带样瘤）是一种非常罕见的起源于肌-腱膜结构的肿瘤。其特征为局部侵袭性生长，有复发倾向但不发生转移。我们报告一例患有左足巨大韧带样瘤的年轻女性。多次手术和放疗导致局部复发。然而，长期使用聚乙二醇化干扰素α-2b进行免疫干预使患者病情有显著临床改善，且经影像学证实疾病稳定。
